Objective: The interest is to determine which type of deviation of the septum creates the greatest air resistance in the nose. The study was organized as an observational trial experience. Subjects that were included had a deformation of nasal septum. The subjects conducted an anterior rhinomanometry test, which was later compared with a control group of individuals who do not have a deformation of the septum. The study was conducted in the clinic for diseases of the ear, nose and throat with head and neck surgery, University Hospital Center Split,. All data were collected on the basis of history, clinical examination and tests anterior rhinomanometry respondents. The tests were made over a period of seven months. Data collection and testing began in November 2013th and finished in June of 2014th year. The collected data cover the following factors: age, gender, previous trauma to the area of the nose and head, earlier operations in the area of the nose and head, symptoms that may be due to deformation of the septum, smoking habits, snoring, type of deformation of the septum, and the very rinomanomety conducted before and after decongestion. Results: The study shows the relationship of 118 respondents, of which 38 members were in the control group and 80 subjects had deformed nasal septum. Subjects were divided according to the type of deformation of the septum into eight groups. Group 0 people without deformation of the septum and groups of 1 to 7 which were the groups of patients with the same type of deformation of the septum. By conducting this study observed a statistically significant difference between the average value of the coefficient of air resistance among patients with deformation of the septum and the control group (p <1%). The difference in rhinomanometry measurements was shown between different types of septal deviation, but statistically significant difference was not confirmed. By conducting decongestion there was a statistically substantial reduction rhinomanometry values in subjects with impaired nasal pass ability (p = 0.6639%). A statistically significant difference was confirmed between rhinomanometry values between patients who sustained violation of the nose or head, and respondents who had no injuries (p = 0.0015%). Conclusion: People who have deformed nasal septum often have disturbances in breathing through the nose. Deformation of the nasal septum provides greater resistance to nasal flow; increased resistance can be measured by rhinomanometry. Although the application of topical anesthetic and decongestant may slightly improve nasal flow, mechanical obstruction still remains a major obstacle for normal breathing through the nose in people with deformed nasal septum.