prikaz prve stranice dokumenta The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study
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master's thesis
The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study
2019. urn:nbn:hr:171:451286
Hagelien, Maximilian
University of Split
School of Medicine

Cite this document

Hagelien, M. (2019). The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:451286

Hagelien, Maximilian. "The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study." Master's thesis, University of Split, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:171:451286

Hagelien, Maximilian. "The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study." Master's thesis, University of Split, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:171:451286

Hagelien, M. (2019). 'The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study', Master's thesis, University of Split, School of Medicine, accessed 05 December 2024, https://urn.nsk.hr/urn:nbn:hr:171:451286

Hagelien M. The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study [Master's thesis]. Split: University of Split, School of Medicine; 2019 [cited 2024 December 05] Available at: https://urn.nsk.hr/urn:nbn:hr:171:451286

M. Hagelien, "The influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study", Master's thesis, University of Split, School of Medicine, Split, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:171:451286

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Metadata
TitleThe influence of peripheral electromagnetic solenoid - type vibration on motor cortical excitability : a navigated transcranial magnetic stimulation study
Title (croatian)Utjecaj periferne elektromagnetske vibracije na motoričku podražljivost kore mozga : navigacijska transkranijalna magnetska stimulacija
AuthorMaximilian Hagelien
MentorMaja Rogić Vidaković (mentor)
Committee memberMaja Valić (predsjednik povjerenstva)
Committee memberJoško Božić (član povjerenstva)
Committee memberRenata Pecotić (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2019-09-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Neuroscience
Abstract
Objectives: Much effort has previously been put towards investigating motor cortical excitability by applying peripheral afferent stimuli in the form of electrical stimulation to the nerves or vibration of the hand muscles. The aim of the present study was to investigate cortical motor excitability in the context of peripheral cutaneous vibration input to the finger. Materials and methods: 11 healthy subjects underwent a conditioning-test (CT) protocol with peripheral vibration of the index finger serving as conditioning, and TMS to M1 serving as test stimulus. Vibration and TMS were separated by randomized inter-stimulus intervals (ISIs) in the range 5-500 ms. Resulting motor evoked potentials (MEPs) were recorded with EMG from the abductor pollicis brevis (APB) muscle, and statistical analysis was performed for its amplitude and latency. Results: Statistically significant suppression of MEP amplitudes in the upper extremity muscle were proven for the ISIs 200, 300, and 400 ms. Conclusion: These findings of suppression of the MEP response at long ISIs are consistent with cortical excitability alterations suggested to result from sensorimotor integration processes following arrival of the afferent sensory volley to the motor cortices.
Abstract (croatian)
Ciljevi: Dosadašnja istraživanja su bila usmjerena na ispitivanje podražljivosti motoričke kore mozga tijekom apliciranja aferentne električne stimulacije živca ili podraživanjem mišića perkutano. Cilj naše studije je bio istražiti podražljivost motoričke kore vibracijskom stimulacijom prsta. Materijali i metode: 11 zdravih ispitanika sudjelovalo je u protokolu u kojemu periferni stimulus (vibracija elektromagnetskog tipa na vrh prsta) prethodi magnetskoj stimulaciji motoričke kore mozga. Interstimulus interval između vibracijske i magnetske stimulacije bio je između 5-500 milisekundi. Motorički evocirani potencijali (MEP) su snimani površinskim elektrodama postavljenim na abductor pollicis brevis mišić ruke. Provedena je statistička analiza u kojoj se evaluirala latencija i amplitude MEP odgovora. Rezultati: Statistička analiza je pokazala značajno smanjenje amplitude MEP odgovora na interstimulus intervalima od 200, 300 i 400 ms. Zaključak: Supresivni učinak MEP odgovora pronađen na specifičnim interstimulus intervalima ide u prilog objašnjenju da je došlo do promjena u podražljivosti kore mozga koje vrlo vjerojatno postoje zbog procesa somatosenzorne integracije koji se događa nakon dolaska afferentnog signala prema motoričkoj kori mozga.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:451286
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-07-05 12:55:57