Objectives: Pharmacovigilance is a set of activities related to preventing, detecting, assessing, understanding and treating drug side effects (ADR) and new knowledge about the harmful effects of drug use. The study aimed to determine whether there are differences in attitudes and knowledge about the importance of reporting drug side effects among students at the School of Medicine in Split. Materials and methods: The research involved 524 students from three integrated study programs (medicine, dental medicine and pharmacy) at the Faculty of Medicine in Split who filled out the Google form. Data were analysed using the Kruskal-Wallis test and the Mann-Whitney U test. Results: Pharmacy students are in the higher, and dental students in the smallest percentage familiar with the concepts of pharmacovigilance (χ2 = 54,242, df = 2, P ˂ 0.001) and HALMED (χ2 = 29,541, df = 2, P ˂ 0.001). There is a difference in attitudes on pharmacovigilance between students who have attended Pharmacology course and those who have not. Conclusion: Students who attended courses at the Department of Pharmacology are better acquainted with the concept of pharmacovigilance and HALMED. Most students think that the study curriculum does not sufficiently cover pharmacovigilance and that they are not well enough prepared to report suspected side effects in their future practice.