Title MORFOLOŠKE PROMJENE TRBUŠNE AORTE POVEZANE S DOBI Title (english) AGE RELATED MORPHOLOGICAL CHANGES OF THE ABDOMINAL AORTA Author Katarina Petrović Mentor Liana Cambj Sapunar (mentor)Granter University of Split Defense date and country 2012, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Cilj istraživanja: Standardiziranim mjerenjem određenih područja trbušne aorte s pomoću
kompjutorizirane tomografije želimo vidjeti postoje li morfološke razlike aorte ovisno o dobi,
spolu, visini, masi i postoji li razlika u mijenjanju morfoloških značajki u gornjem i donjem
dijelu trbušne aorte.
Ustroj istraživanja: Presječno istraživanje.
Mjesto istraživanja: Klinički zavod za dijagnostičku i intervencijsku radiologiju Kliničkog
Bolničkog Centra Split.
Sudionici: U istraživanju sudjeluje 46 ispitanika koji su stariji od dvadeset godina, a kojima
je u razdoblju od 1. veljače do 30. travnja 2012. godine urađena kompjutorizirana tomografija
trbuha zbog bilo koje bolesti ili traume.
Glavne mjere ishoda: Promjeri i duljine trbušne aorte u određenim područjima mjerenja.
Rezultati: Trbušna aorta se u muškaraca i žena s dobi širi, ali ne mijenja svoju duljinu
(r=0,58; P=0,704). Muškarci imaju dulju (F=6,6; P=0,014) i širu trbušnu aortu u odnosu na
žene: najširi infrarenalni promjer je veći u muškaraca nego u žena (F=15; P<0,001) . Indeks
tjelesne mase nije povezan s promjerom i duljinom trbušne aorte (r=0,05; P=0,748). Nismo
dokazali značajne razlike u povećanju promjera s dobi između gornjeg (područje izlazišta
velikih visceralnih ogranaka) i donjeg, infrarenalnog dijela trbušne aorte: promjer aorte uz
donji rub desne bubrežne aorte je u dobnoj skupini ≥60 godina za 0,45 cm veći nego u dobnoj
skupini ≤39 godina (Bonferoni: P<0,001); promjer aorte u području djelišta je u dobnoj
skupini ≥60 godina za 0,39 cm veći nego u dobnoj skupini ≤39 godina (Bonferoni: P=0,015).
Zaključak: Dokazali smo da se trbušna aorta s dobi morfološki mijenja i da je dulja i šira u
muškaraca. Nismo dokazali morfološke razlike ovisno o dobi između gornjeg i donjeg dijela
trbušne aorte. Za dokazivanje ovih razlika potrebna su daljnja istraživanja s većim brojem
ispitanika.
Abstract (english) Objective: To examine the relationship between morphological characteristics of the
abdominal aorta and age, sex, body height and weight by using standardized measurement of
clearly defined anatomic areas of the abdominal aorta on computed tomography. We tested
our hypotesis that due to different hystological morphology between the upper and the
infrarenal part of the abodminal aorta. There are also age related differences in dilation
between these two distinct anatomical areas of the abodminal aorta.
Design: Cross-sectional study.
Settings: The study was performed in Clinical Unit of Diagnostic and Interventional
Radiology University Hospital of Split.
Participants: The study included 46 participants older than twenty years who underwent
computed tomography of the abdomen between 1 February and 30 April 2012.
Main outcome measures: Diameters and lengths of the abdominal aorta in a clearly defined
areas of measurements.
Results: Men have larger (F=6,6; P=0,014) and wider aortas than women. The maximum
infrarenal aortic diameter is wider in men than in women (F=15; P<0,001). Aortic diameter
increases with age in both, men and women, but the length doesn't increse (r=0,58; P=0,704).
Body mass index isn't associated with diameter and length of the abdominal aorta (r=0,05;
P=0,748). We haven't found the differences in diameter changes between the visceral and
infrarenal part of the abdominal aorta: the diameter of aorta at the level of the right renal
artery is in participans age ≥60 years 0,45 cm wider than in participans age ≤39 years
(Bonferoni; P=0,013); the diameter of aorta at the bifurcation is 0,39 cm wider in participans
age ≥60 years than in participans age ≤39 years (Bonferoni; P=0,015).
Conclusions: Our results show that the aobdominal aorta changes morphologicaly with age
and it is wider in men. However, we didn't prove that there are age related differences in
morphological changes of the abdominal aorta between the upper and infrarenal part. Further
and larger studies are needed to determine this relationship.
Keywords
Abdominalna aorta
Aneurizma abdominalne aorte
Stentovi
Keywords (english)
Abdominal Aorta
Aortic Aneurysm Abdominal
Stents
Language croatian URN:NBN urn:nbn:hr:171:814518 Study programme Title: Medicina Type of resource text File origin Born digital Access conditions Restricted access Terms of use Created on 2016-05-19 09:54:51
