Objective: To determine the connection between discordant twin growth and incidence of preterm birth. Design: Retrospectively analyzed delivery room birth protocols and medical histories in period from January 1st,2013 to December 31st,2015. Settings and participants: The study included 217 women with twin pregnancies. 13 women were excluded from the sample due to death of one or both infants, or lack of medical documentation. Sample was divided in two groups- pregnancies with and without discordant twin growth. Main Outcome Measures: Pregnancy duration and difference in infants' birthweight [(birthweight of lighter twin- birthweight of heavier twin)/ birthweight of heavier twin] expressed in percent. Results: Average age of woment pregnant with discordant twins was 31,4 ±5,6 years, and of those pregnant with concordant twins 30,93 ±4,83 years. Average age of women who conceived by assisted reproductive technology (ART) was 34,56 ±5,43 years, and of those who spontaneously conceived 30,63 ±4,56 years. Preterm birth was significantly more frequent in group of women pregnant with discordant twins (p= 0,0295). Twins with discordant growth had Apgar score ≤7 significantly more frequent than concordant twins (p=0,0047). There was no significant difference between two groups regardless of method of conception, as well as in groups of women who conceived spontaneously and those who conceived by ART. There was no significant difference in birthweight between groups of discordant and concordant twins.. Preeclampsia was significantly more frequent in women of age 36 and more (p=0,03132). Preterm births more frequently underwent Caesarean section than term births (p=0,02893). There was no significant difference in birth termination method between groups of women divided by conception method. Method of conception has no significant impact on occurence of discordant fetal growth in twin pregnancies. Conclusions: Preterm birth was significantly more frequent in group of women with discordant fetal growth twin pregnancy. There was no significant difference between two groups regardless of birth termination method. Twins with discordant growth had Apgar score ≤7 significantly more frequent than concordant twins. There was no significant difference between groups of women who conceived spontaneously and those who conceived by ART regardless of method of conception. Preeclampsia was significantly more frequent in women of age 36 and more pregnant with twins.