Title PONDERALNI INDEKS U DJECE SA SINDROMOM DOWN Title (english) PONDERAL INDEX IN CHILDREN WITH DOWN SYNDROME Author Marina Bešlić Mentor Ivana Unić (mentor)Committee member Martina Šunj (predsjednik povjerenstva) Committee member Branka Polić (član povjerenstva) Committee member Slavica Kozina (član povjerenstva)Granter University of Split Defense date and country 2018, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Cilj istraživanja: Cilj ovoga istraživanja bio je odrediti vrijednosti porođajne mase, duljine i ponderalnog indeksa novorođenčadi sa sindromom Down, usporediti kategorizaciju navedenih parametara prema različitim normama i utvrditi vrijednosti ponderalnog indeksa u ovoj populaciji. Ispitanici i metode: U istraživanje je uključeno 141 novorođenče s dijagnozom sindroma Down rođeno u Klinici za ženske bolesti i porode KBC-a Split u razdoblju od 1990. do 2015. godine. Retrospektivnom analizom rađaonskog protokola kod svih ispitanika prikupljeni su sljedeći podaci: spol, gestacijska dob, porođajna masa, porođajna duljina i ponderalni indeks. Vrijednosti porođajne mase i duljine kategorizirane su prema normama za zdravu djecu i djecu sa sindromom Down, a vrijednosti ponderalnog indeksa prema normama za gestacijsku dob. Rezultati: U promatranome razdoblju rođeno je 141 dijete sa sindromom Down. Među ispitivanom novorođenčadi bilo je 52,5% muške i 47,5% ženske djece. Prema normama za sindrom Down 78,7% ispitanika ima za dob primjerene vrijednosti porođajne mase, a 82,3% ima za dob primjerene vrijednosti porođajne duljine. Vrijednost ponderalnog indeksa u 88,7% ispitanika je u rasponu od 10. – 90. centile i odgovara normalnim vrijednostima za gestacijsku dob. Novorođenčad malene, za dob primjerene i velike porođajne mase statistički se značajno razlikuje u vrijednostima porođajne mase, duljine i ponderalnog indeksa neovisno o tome kategorizira li se porođajna masa prema normama za zdravu djecu ili djecu sa sindromom Down. Zaključci: Kategorizacija porođajne mase i duljine ispitanika znatno se razlikuje ovisno o primijenjenim normama. Korištenjem za sindrom specifičnih normi većina djece svrstava se u skupinu za dob primjerenih vrijednosti porođajne mase i duljine, a broj malenih i velikih za dob je manji u odnosu na kategorizaciju prema normama za zdravu djecu. Većina ispitanika ima normalne vrijednosti ponderalnog indeksa. Za postavljanje sumnje na intrauterini zastoj u rastu potrebna je ispravna kategorizacija prema porođajnoj masi te poznavanje referentnih vrijednosti ponderalnog indeksa za sindrom Down u specifičnoj populaciji.
Abstract (english) Objectives and background: The aims of this study were to determine the values of birth weight, length and ponderal index of newborn infants with Down syndrome, to compare the categorization of these parameters according to different standards and to determine ponderal index values in this population. Patients and methods: The study included 141 newborns with the diagnosis of Down syndrome born at the Department of Gynecology and Obstetrics of University Hospital of Split from 1990. to 2015. Delivery room birth protocols were retrospectively reviewed and following data were collected: sex, gestational age, birth weight, birth length and ponderal index. The values of birth weight and length are categorized according to the standards for healthy children and children with Down syndrome. Ponderal index values are categorized according to gestational age standards. Results: In the observed period, 141 children with Down syndrome were born. Among the examined infants 52.5% were male and 47.5% were female. According to the standards for Down syndrome, 78.7% of subjects are classified as appropriate for gestational age (AGA) by their birth weight and 82.3% are classified as appropriate for age (AGA) by birth length. Ponderal index value is within the range of 10th to 90th percentile in 88.7% of subjects and corresponds to normal gestational age values. Newborn babies classified as small, appropriate and large for gestational age by their birth weight are significantly different in birth weight, length and ponderal index, regardless of the standards used for birth weight classification. Conclusions: Birth weight and birth length categorization is significantly different depending on the standards applied. By using syndrome specific standards most children are categorized in the appropriate for age group by their birth weight and length. The number of children classified as small or large for gestational age is lower when we use Down syndrome standards instead of standards for healthy children. Most of the subjects have normal ponderal index values. In order to suspect intrauterine growth restriction, correct birth weight categorization and ponderal index standards for Down syndrome in a specific population are required.
Keywords
Sindrom Down
Novorođenče
Antropometrija
Keywords (english)
Down Syndrome
Infant Newborn
Anthropometry
Language croatian URN:NBN urn:nbn:hr:171:362480 Study programme Title: Medicina Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2018-10-22 06:11:29
