prikaz prve stranice dokumenta Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients
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master's thesis
Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients
2019. urn:nbn:hr:171:350147
Pedersen, Nina Rani
University of Split
School of Medicine
Neuroscience

Cite this document

Pedersen, N. R. (2019). Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:350147

Pedersen, Nina Rani. "Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients." Master's thesis, University of Split, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:171:350147

Pedersen, Nina Rani. "Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients." Master's thesis, University of Split, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:171:350147

Pedersen, N. R. (2019). 'Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients', Master's thesis, University of Split, School of Medicine, accessed 11 April 2025, https://urn.nsk.hr/urn:nbn:hr:171:350147

Pedersen NR. Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients [Master's thesis]. Split: University of Split, School of Medicine; 2019 [cited 2025 April 11] Available at: https://urn.nsk.hr/urn:nbn:hr:171:350147

N. R. Pedersen, "Comparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients", Master's thesis, University of Split, School of Medicine, Split, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:171:350147

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TitleComparison of subjective sleep quality and daytime sleepiness with whole-night polysomnography findings in sleep apnea patients
Title (croatian)Usporedba subjektivne kvalitete spavanja i dnevne pospanosti s nalazima cjelonoćne polisomnografije u pacijenata s opstrukcijskom apnejom tijekom spavanja
AuthorNina Rani Pedersen
MentorIvana Pavlinac Dodig (mentor)
Committee memberRenata Pecotić (predsjednik povjerenstva)
Committee memberJoško Božić (član povjerenstva)
Committee memberMaja Valić (član povjerenstva)
GranterUniversity of Split
School of Medicine
(Neuroscience)
Split
Defense date and country2019-07-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Neuroscience
Abstract
Objectives: Obstructive sleep apnea (OSA) is a disorder characterized by repetitive cessations of breathing during sleep. One of the most prominent symptoms of OSA is excessive daytime sleepiness, associated with micro arousals from sleep which are caused by respiratory events. Another feature of the OSA linked to respiratory related arousals might be impaired sleep architecture resulting in decreased subjective sleep quality. The main aim of this research was to assess and compare the... More subjective sleep quality and daytime sleepiness and objective whole-night polysomnography findings in OSA patients. Patients and methods: A total of 317 adult OSA patients from the Split Sleep Medicine Center, with an age range from 18 to 82 years, were included in this study. All the patients filled in the questionnaires: Epworth sleepiness scale (ESS), assessing daytime sleepiness, and Pittsburgh Sleep Quality Index (PSQI), assessing subjective sleep quality. Following completion of the questionnaires, the patients underwent whole-night polysomnography. Results: Sleep architecture changed with OSA severity, with an increased amount of sleep stage N2 (66.41 ± 11.93% in mild OSA, 69.12 ± 11.43% in moderate OSA and 73.45 ± 14.74% of sleep stage N2 in severe OSA, F = 8.635, P < 0.001) and decreased amount of deep sleep stage N3 in more severe forms of OSA (11.67 ± 8.89 % in mild OSA, 11.10 ± 7.35% in moderate OSA and 6.88 ± 7.63 in severe OSA, F = 12.701, P < 0.001). There was also a correlation between OSA severity and excessive daytime sleepiness assessed by ESS (r = 0.25, P < 0.001). Patients who had poorer sleep efficiency had worse subjective sleep quality assessed by PSQI (r = -0.21, P = 0.001). There were no statistically significant differences in sleep architecture among patients with good and bad sleep quality according to PSQI (P > 0.05), and among those with normal and excessive daytime sleepiness, according to ESS (P > 0.05). Conclusions: The obtained results demonstrated that OSA severity was associated with an impairment of the sleep architecture and with more pronounced excessive daytime sleepiness. Sleep efficiency, but not the sleep architecture of OSA patients correlated with subjective sleep quality assessed by PSQI. However, no differences in sleep architecture among OSA patients with and without excessive daytime sleepiness assessed by ESS were found. Less
Abstract (croatian)
Ciljevi: Opstrukcijska apneja tijekom spavanja (OSA) poremećaj je obilježen ponavljanim prekidima disanja tijekom spavanja. Jedan od najistaknutijih simptoma OSA-e je prekomjerna dnevna pospanost, povezana s mikrobuđenjima koja su uzrokovana respiratornim događajima. Još jedna značajka OSA-e izazvana buđenjima može biti narušena arhitektura spavanja koja bi mogla rezultirati smanjenom subjektivnom kvalitetom spavanja. Glavni cilj ovog istraživanja bio je procijeniti i usporediti... More subjektivnu kvalitetu spavanja i dnevnu pospanost te objektivne polisomnografske nalaze u OSA bolesnika. Pacijenti i postupci: Ukupno 317 odraslih OSA pacijenata iz splitskog Centra za medicinu spavanja, u dobi od 18 do 82 godine, uključeno je u ovu studiju. Svi pacijenti popunili su upitnike: Epworthovu ljestvicu pospanosti (ESS) koja procjenjuje dnevnu pospanost i Pittsburghški indeks kvalitete spavanja (PSQI) koji procjenjuje subjektivnu kvalitetu spavanja. Nakon popunjavanja upitnika, pacijenti su podvrgnuti cjelonoćnoj polisomnografiji. Rezultati: Težina OSA-e utjecala je na arhitekturu spavanja, posebice povećanjem količine N2 stadija spavanja (66,41 ± 11,93% u blagoj OSA-i, 69,12 ± 11,43% u umjerenoj OSA-i i 73,45 ± 14,74% u teškoj OSA-i; F = 8,635, P < 0.001) i smanjenjem količine dubokog spavanja N3 u težim oblicima OSA-e (11,67 ± 8,89% u blagoj OSA-i, 11,10 ± 7,35% u umjerenoj OSA-i i 6,88 ± 7,63 u teškoj OSA-i; F = 12,701, P < 0.001). Postojala je i korelacija između težine OSA-e i prekomjerne dnevne pospanosti procijenjene pomoću ESS (r = 0,25, P < 0.001). Lošija subjektivna kvaliteta spavanja procijenjena pomoću PSQI bila je povezana s manjom učinkovitošću spavanja (r = -0,21, P = 0,001). Nije bilo statistički značajnih razlika u arhitekturi spavanja u bolesnika s dobrom i lošom kvalitetom spavanja prema PSQI-u (P > 0,05), te među onima s normalnom i prekomjernom dnevnom pospanošću, prema ESS-u (P > 0,05). Zaključci: Dobiveni rezultati pokazali su da je težina OSA-e povezana s narušenom arhitekturom spavanja i s izraženijom dnevnom pospanošću. Učinkovitost spavanja, ali ne i arhitektura spavanja OSA bolesnika bila je u korelaciji sa subjektivnom kvalitetom spavanja procijenjenom pomoću PSQI-ja. Međutim, nisu nađene razlike u arhitekturi spavanja u OSA bolesnika sa i bez prekomjerne dnevne pospanosti procijenjene pomoću ESS. Less
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:350147
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-07-09 13:10:23
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