OBJECTIVES: To determine the number of patients with keratoacanthoma in the Clinical Centre of Split in a period of 5 years, the difference between number of men and women with this tumor, in which year of these five we can find the most cases of our keratoacanthomas and under which clasiffication of diseases we can find them. RESULTS: We have found out the number of 99 patients with keratoacanthoma in a period of 5 years, which is an incidence of 144/100000, so we have showed that our results are very similar to the incidence of keratoacanthoma in American white population (106/100000). We have found out that keratoacanthoma appears more in men than in women, most of them appeared in the year of 2011. The most patohistological results of our patients were made in the month of February, which probably means that patients with keratoacanthoma have this skin tumor for many years and they often decide to get rid of it during the winter, when it is usually the best time for the elective surgical intervention. CONCLUSION: This retrospective study shows the similar incidence of this skin tumor in our population and in the world white population. The problem is that the diagnose of keratoacanthoma is usually very similar to the diagnose of the spinocellular carcinome because they have many similar macroscopic and microscopic characteristics. So, it is important to make more scientific studies about this skin tumor, especially to find out whether Keratoacanthoma is asocciated to some other chronic diseases of our patients. It would also be necessary to find out if keratoacanthoma is hidden under some more diagnosis of the diseases in the Clinical Centre of Split.