Title Procjena povezanosti depresije i povećanog kardiovaskularnog rizika
Title (english) Assessment of the association between depression and increased cardiovascular risk
Author Loriana Marović
Mentor Ivančica Pavličević (mentor)
Committee member Ivana Mudnić (predsjednik povjerenstva)
Committee member Shelly Pranić (član povjerenstva)
Committee member Ivančica Pavličević (član povjerenstva)
Granter University of Split School of Medicine Split
Defense date and country 2020-02-07, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Public Health and Health Care Family Medicine
Abstract Ciljevi istraživanja: Utvrditi postoji li povezanost između pojave depresije i povećanog kardiovaskularnog rizika, utvrditi da li je kardiovaskularni rizik veći kod pacijenata oboljelih od depresije negoli u pacijenata koji boluju od kamenaca mokraćnog mjehura.
Ispitanici i metode: Podatci su prikupljeni iz medicinske dokumentacije jedne ordinacije obiteljske medicine u Splitu. Ukupno je uključeno 68 pacijenata, od kojih je 36 bilo s depresijom (intervencijska skupina) i 37 s urolitijazom (kontrolna skupina), kod kojih je u razdoblju između 2012. i 2017. godine prvi put dijagnosticirana jedna od ove dvije bolesti. Svakog pacijenta se pratilo jednak vremenski period (365 dana) od dijagnoze jedne od ove dvije bolesti. Statistička analiza je rađena u statističkom programu STATISTICA 12.
Rezultati: Nije utvrđeno postojanje statistički značajne razlike za analizirane parametre (kolesterol, HDL, sistolički tlak, dijastolički tlak, liječenje tlaka, pušenje i dijabetes) između interventne i kontrolne skupine ni na početku ni na kraju istraživanja. Testiranjem nije utvrđeno postojanje statistički značajne razlike u razini kardiovaskularnog rizika između interventne i kontrolne skupine (Z=1,40; p=0,161). Tokom istraživanja došlo je do porasta kardiovaskularnog rizika i u intervencijskoj (Z=5,00; p<0,001) i u kontrolnoj skupini (Z=5,00; p<0,001). U interventnoj skupini je zabilježen značajno veći broj posjeta liječniku i zbog pogoršanja (Z=2,29; p=0,022) i zbog kontrole (t=2,26; p=0,022) u usporedbi s kontrolnom skupinom.
Zaključci: Razina kardiovaskularnog rizika nije veća kod pacijenata oboljelih od depresije nego kod pacijenata s urolitijazom. Ove dvije ispitivane grupe imale su slične vrijednosti za sve ispitivane parametre. Kod pacijenata s depresijom zabilježen je značajno veći broj posjeta liječniku u odnosu na pacijente oboljele od urolitijaze.
Abstract (english) The aim of the research: To determine whether there is an association between depression and increased cardiovascular risk, to determine whether cardiovascular risk is higher in patients with depression than in patients with bladder stones.
Patients and methods: The data were collected from the medical records from the one family physician’s office in Split. A total of 68 patients were enrolled, 36 of whom were depressed (intervention group) and 37 with urolithiasis (control group), who were first diagnosed with one of these two diseases between 2012 and 2017. Each patient was followed for an equal period of time (365 days) from the diagnosis of one of these two diseases. Statistical analysis was performed in the statistical program STATISTICA 12.
Results: There was no statistically significant difference for the analyzed parameters (cholesterol, HDL, systolic pressure, diastolic pressure, pressure treatment, smoking, and diabetes) between the intervention and control groups at the beginning and end of the study. No significant difference was found in the analysis in the level of cardiovascular risk between the intervention and control groups (Z = 1,40; p = 0,161). The increase in the level of cardiovascular risk reached statistical significance in both the intervention group (Z = 5,00; p <0,001) and the control group (Z = 5,00; p <0,001). In the intervention group was observed significantly more visits to the physician, both due to worsening (Z = 2,29; p = 0,022) and due to control (t = 2,26; p = 0,022) compared to the control group.
Conclusion: The level of cardiovascular risk is not higher among patients with depression than among patients with urolithiasis. These two test groups had similar values for all the parameters tested. In patients with depression, there was a significantly higher number of doctor visits compared to patients with urolithiasis.
Keywords
Depresija
Kardiovaskularne bolesti
Čimbenici rizika
Urolitijaza
Keywords (english)
Depression
Cardiovascular Diseases
Risk Factors
Urolithiasis
Language croatian
URN:NBN urn:nbn:hr:171:060241
Study programme Title: Pharmacy Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2020-06-08 10:42:05