Code book: Frame 0-Negative frame 1- Positive frame Group Gender 1- Male 2- Female Age (in years) Education (highest degree achieved) 1- elementary school 2- high school 3- currently enrolled at university 4- graduated in college 5- university graduate 6- PhD Information sources (marked as 1 for every source): a- Internet b- family and friends c- books d- family doctor e- something else Internet sources (each marked as 1): First page on Google Forums Hospital websites Local specialized websites International specialized websites Scientific articles Email to doctors on Internet portals Comprehension questions about PLS-s: Each correct answer 1 point, incorrect 0; maximum 4 per pls (8 in total) Perceived effectiveness of treatment total Sum of scores from three PLS-s Desire that treatment be prescribed by family doctor total Sum of scores from three PLSs Readiness to use the treatment total Sum of scores from three PLSs Comprehension total Sum of scores from three PLSs Additional information: text Numeracy total: Maximum five points from five tasks