| Abstract | Objectives: The aim of this study is to investigate the frequency of gastrointestinal biopsies performed on pediatric patients at University Hospital of Split during a three-year time period, from 2017 to 2019. From this investigation, we aimed to determine both the most common clinical and final diagnosis accompanying the biopsy tissue. Further, average age of diagnosis and differences in frequency of particular diagnoses according to patient gender were explored.
Materials and methods: A retrospective analysis was conducted on medical records of pediatric patients, up to the age of 18 years, who underwent gastrointestinal endoscopy with subsequent obtaining of tissue biopsy from the beginning of January 2017 to the end of December 2019 at the Pediatrics Department of University Hospital of Split. Data obtained from the archives of these patients included patient date of birth, gender, clinical diagnosis, type of gastrointestinal endoscopy performed, the number and type of tissue samples obtained by biopsy, and final diagnosis based on pathohistological report. Statistical analysis was performed using MedCalc.
Results: 336 pathohistological reports were collected from this three-year time period. Of these pediatric patients, 155 (46.1%) were boys and 181 (53.9%) were girls, with the average age of the patient being 11 years. 281 gastroscopies (83.6%), 48 colonoscopies (14.3%), and 7 combined gastroscopy and colonoscopy (2.1%) performed in the same act were performed, which shows statistical significance (P<0.0001). The most common clinical diagnoses indicating endoscopy and pathohistological analysis were abdominal colic (17.3%) and category “other” (17.6%), with the least common clinical diagnoses being chronic gastritis and duodenitis (0.3%), which is statistically significant (P<0.0001). The most common final pathohistological result was descriptive (54.5%). There was no statistical significance in the pathology report between male and female patients (p=0.187).
Conclusion: During this three-year time period, pediatric patients undergoing gastrointestinal endoscopic procedures were more often females. Among the most frequent complaints were abdominal colic, as well as others, with these being indications for endoscopy and tissue biopsy, such that gastroscopy was the most commonly performed procedure. Pathohistological analyses presented a final diagnosis most often as a descriptive report. |
| Abstract (croatian) | Ciljevi: Cilj ovog istraživanja je odrediti učestalost gastrointestinalnih biopsija u pedijatrijskoj populaciji u KBC Split u trogodišnjem razdoblju, od 2017 do 2019. Također, cilj je bio ustanoviti najučestalije kliničke uputne dijagnoze, te konačne patohistološke dijagnoze, i utvrditi prosječnu dob prilikom postavljanja dijagnoze, te postoje li razlike u učestalosti kliničkih i patohistoloških dijagnoza obzirom na spol pacijenata.
Materijali i metode: Istraživanje je retrospektivno i opservacijsko. Podatci su dobiveni pregledom patohistoloških nalaza Odjela Patologije, Kliničkog zavoda za patologiju, sudsku medicine i citologiju KBC Split, i medicinske dokumentacije pedijatrijskih pacijenata Odjela Pedijatrije iste bolnice, kojima je u razdoblju od siječnja 2017. do prosinca 2019. godine uzeta biopsija tkiva prilikom endoskopske pretrage gastrointestinalnog trakta. Zabilježeni su sljedeći podatci: datum rođenja, spol, klinička dijagnoza, vrsta endoskopske pretrage, broj i vrsta uzetih uzoraka tkiva, a iz patohistoloških nalaza konačna dijagnoza i histološke karakteristike uzoraka.
Rezultati: U trogodišnjem razdoblju pregledano je 336 patohistoloških nalaza pedijatrijskih pacijenata od kojih je bilo 155 (46,1%) dječaka i 181 (53,9%) djevojčica, prosječna dob je bila 11 godina. Učinjena je 281 gastroskopija (83,6%), 48 kolonoskopija (14,3%), i 7 gastroskopija i kolonoskopija u istom aktu (2,1%) što je bilo statistički značajno (P<0,0001). Abdominalne kolike (17,3%) i kategorija “ostalo” (17,6%) su bile najčešće uputne kliničke dijagnoza, dok su najrjeđe uputne dijagnoze bile kronični gastritis i duodenitis (0,3%), što je bilo statistički značajno (P<0,0001). Konačna patohistološka dijagnoza je najčešće bila opisna (54,5%). Nije bilo statistički značajne razlike u patohistološkoj dijagnozi obzirom na spol pacijenata (p=0,187).
Zaključak: U trogodišnjem istraživanom razdoblju pedijatrijski pacijenti koji su podvrgnuti endoskopskim pretragama gastrointestinalnog trakta su češće bile djevojčice. Najčešća uputna dijagnoza i razlog upućivanja pacijenta na pretragu su bile abdominalne kolike i skupina “ostalih” dijagnoza. Gastroskopija je najučestalija pretraga, a konačni patohistološki nalaz je u većini slučajeva bio opisne prirode. |
