Objectives: The expression and localization of Greb1l in the nephrons of yotari (Dab1-/-) and wildtype (Dab1+/+) mice was analyzed to further develop its suggested importance in mammal kidneys overall, but also its significance particularly in yotari mice nephrons. Materials and methods: yotari and wildtype mice were sacrificed on the 13.5th embryonal day, and 4th and 14th postnatal day. Paraffin embedded kidney tissue sections were analyzed by immunofluorescence using Greb1l antibodies. Kidney structures were then examined by fluorescence microscope. The percentages of positive cells between each group were compared and analyzed by a Kruskal-Wallis-test, followed by a t-test. Results: In 14D kidneys of both genotypes, DCT was the structure with the highest percentage of Greb1l immunoreactive cells, particularly in the yotari group (p<0.01). The highest percentage of positive Greb1l cell expression of the 4D kidney was in the wildtype genotype for both DCT and glomeruli (p<0.01). Minimal positive Greb1l cell expression of E13.5 kidney was in the glomeruli of both genotypes, with no statistical significance. No Greb1l positive cells were observed in PCT and DCT at this stage in both genotypes. Conclusion: The expression pattern of Greb1l in the nephron structures of the two mouse genotypes implicates the potential importance of Greb1l in DCT in 14D kidney, especially in yotari mice. Overall, the wildtype 4D nephron showed significantly higher expression of Greb1l in DCT and glomeruli, suggesting its potential importance at this stage of kidney development. Lastly, there was almost non-existent Greb1l expression in all structures of both genotypes in E13.5 kidney, implicating that Greb1l expression pattern is more important in later stages of kidney development. Overall, it seems how kidney developmental pattern in yotari mice is delayed in comparison to wildtype group, which is a possible explanation for the discrepancy.