Title Učestalost orofacijalnih trauma u oboljelih od epilepsije
Title (english) Incidence of orofacial trauma in patients with epilepsy
Author Dora Mimica
Mentor Ivana Medvedec Mikić (mentor)
Committee member Ivan Galić (predsjednik povjerenstva)
Committee member Danijela Kalibović Govorko (član povjerenstva)
Committee member Lidia Gavić (član povjerenstva)
Granter University of Split School of Medicine (Endodoncy and restorative dentistry) Split
Defense date and country 2021, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Dental Medicine Endodonics and Restorative Dentistry
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Neurology
Abstract Cilj: Cilj ovog istraživanja bio je utvrditi koliko je česta pojavnost orofacijalnih ozljeda u pacijenata oboljelih od epilepsije budući da su takvi pacijenti znatno skloniji ozljedama jer tijekom epileptičnog napadaja često dolazi do gubitka svijesti.
Materijali i metode: U istraživanju je sudjelovalo 56 ispitanika koji su ispunjavali upitnike. Upitnici su podijeljeni na Klinici za neurologiju pri Kliničkom bolničkom centru u Splitu i preko Hrvatske udruge za epilepsiju od ožujka do lipnja 2021. godine. Ispitanici su trebali odgovoriti na 24 pitanja koja su se odnosila na njihovu osnovnu bolest i moguće ozljede u usnoj šupljini i na licu koje su pretrpjeli. Nakon prikupljanja svih ispunjenih upitnika napravljena je statistička analiza dobivenih podataka.
Rezultati: Ispitanici koji boluju od tipova epilepsije kod kojih dolazi do gubitka svijesti i tonusa mišića (generalizirani i sekundarno generalizirani) doživjeli su više trauma orofacijalnog područja. Ispitanici koji ne mogu predosjetiti napadaj (58,9%) imali su teže ozljede tijekom napadaja dok su ispitanici koji dulje boluju od epilepsije imali su više trauma. Antiepileptici, glavna terapija u liječenju epilepsije, lijekovi su koji imaju puno nuspojava koje utječu na učestalost trauma – umor, smušenost i dezorijentiranost. Ozljede su češće u bolesnika koji ne uzimaju redovito terapiju i koji uzimaju više vrsta antiepileptika. Antiepileptici neizravno utječu na zdravlje usne šupljine tako što mnogi uzrokuju hiperplaziju gingive, gingivits i kserostomiju, što može znatno ugroziti oralno zdravlje. Većina ispitanika je informirala svog liječnika dentalne medicine da boluju od epilepsije i da primaju terapiju za liječenje epilepsije. Očekivano, zubi koji su najčešće bili ozlijeđeni su gornji središnji sjekutići, a potom gornji lateralni sjekutići. Tip ozljede koji je najčešći je nekomplicirana fraktura krune i subluksacija. Čak 50% ispitanika imalo je prijelom nosne kosti, a 37,5% je imalo prijelom donje čeljusti. Od mekotkivnih ozljeda, najviše ispitanika je doživjelo ugriz u jezik što je česta pojava tokom toničko-kloničkih napadaja.
Zaključak: Orofacijalne ozljede česte su u oboljelih od epilepsije, posebice ako imaju generalizirani i sekundarno generalizirani tip epilepsije. Lijekovi koji se koriste u liječenju ove bolesti nose sa sobom brojne nuspojave koje negativno djeluju na zdravlje pojedinca i na njegovo oralno zdravlje.
Abstract (english) Objectives: The purpose of this research was to evaluate the incidence of orofacial trauma in epilepsy patients given that patients with epilepsy are significantly more prone to injury beacause an epileptic seizure often causes loss of consciousness.
Materials and methods: A total of 56 subjects participated in the research by completing questionnaires. The questionnaires were distributed at the Neurology Department of the University Hospital Centre Split and through the Croatian Association for Epilepsy from March to June 2021. Subjects were asked to answer 24 questions related to their underlying illness and possible oral and maxillofacial trauma they had suffered. After the answers were obtained, a statistical analysis of the data was performed.
Results: Subjects who suffer from the types of epilepsy which are associated with loss of consciousness and a loss of muscle tone (generalized tonic-clonic and generalized seizures) experienced more orofacial trauma. Subjects who cannot sense a seizure coming (58,9%) had more severe injuries, while subjects with longer epilepsy duration experienced more trauma.
Antiepileptic drugs, which are the main therapy in the treatment of epilepsy, have many side effects affecting the frequency of trauma - fatigue, confusion and disorientation. Injuries are more common in patients who do not take therapy regularly as well as patients who receive multitherapy. Antiepileptic drugs indirectly affect oral health. Many of them cause gingival hyperplasia, gingivitis, and xerostomia, which can significantly compromise oral health. Most subjects informed their dentist that they suffered from epilepsy and were receiving treatment. As expected, the most frequently injured teeth were the upper central incisors, followed by the upper lateral incisors. The most common type of injury is simple crown fracture followed by subluxation. Even 50% of subjects experienced nasal bone fracture and 37,5% had
mandibular fracture. Among soft tissue injuries, most subjects experienced tongue biting, which is common during tonic-clonic seizures.
Conclusion: Orofacial injuries are common in patients with epilepsy, especially if they have generalized or secondary generalized epilepsy. Drugs used in the treatment of this condition have numerous side effects and may be associated with the risk of adverse effects on individuals’ general health as well as their oral health.
Keywords
Ozljede zuba
Epilepsija
Keywords (english)
Tooth Injuries
Epilepsy
Language croatian
URN:NBN urn:nbn:hr:171:678062
Study programme Title: Dental Medicine Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2021-08-30 12:16:29