Objectives: The aims and objectives of this study were to compare the baseline characteristics of patients treated for heart failure with reduced (HFrEF), mildly-reduced (HFmrEF) and preserved (HFpEF) ejection fraction according to data obtained from the Croatian registry for patients with heart failure. Materials and Methods: This retrospective study included a total of 869 patients hospitalised with heart failure of which 322 had HFpEF, 150 had HFmrEF and 397 had HFrEF. All patient data was extracted from the Croatian registry for patients with heart failure and analyzed using Microsoft Excel and GraphPad Prism. Results: Of the 322 patients who were treated for HFpEF, 55% were females. The average age of patients treated with HFrEF was 68 years whereas the average age in HFmrEF and HFpEF was 72 and 73 years respectively. The most common comorbidity in patients treated with HFpEF was coronary artery disease (77%), arterial hypertension (68%), and pulmonary hypertension (55%). The most common comorbidities in patients with HFmrEF were coronary artery disease (85%), arterial hypertension (68%), and atrial fibrillation (57%). The most common comorbidities in patients with HFrEF were coronary artery disease (77%), arterial hypertension (49%), and atrial fibrillation (45%). The most commonly prescribed medications in HFpEF were diuretics (78%), ACEi (63%), and beta-blockers (54%). The most commonly prescribed medication in HFmrEF were diuretics (70%), beta-blockers (65%), and ACEi (61%). The most commonly prescribed medication in HFrEF were diuretics (82%), Betablockers (65%), and ACEi (44%). Conclusions: Patients treated for HFpEF were more likely to be women and more elderly. The most common among all heart failure groups were coronary artery disease and arterial hypertension. Regarding medical management, beta-blockers were more often prescribed to HFpEF patients whereas calcium channel blockers were more often prescribed to HFmrEF and HFpEF patients.