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master's thesis
Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika
2023. urn:nbn:hr:171:171280
Bašić, Mia
University of Split
School of Medicine

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Bašić, M. (2023). Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:171280

Bašić, Mia. "Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:171280

Bašić, Mia. "Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:171280

Bašić, M. (2023). 'Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika', Master's thesis, University of Split, School of Medicine, accessed 03 April 2025, https://urn.nsk.hr/urn:nbn:hr:171:171280

Bašić M. Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika [Master's thesis]. Split: University of Split, School of Medicine; 2023 [cited 2025 April 03] Available at: https://urn.nsk.hr/urn:nbn:hr:171:171280

M. Bašić, "Koristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika", Master's thesis, University of Split, School of Medicine, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:171:171280

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Metadata
TitleKoristi i rizici primjene odabranih dodataka prehrani u onkoloških bolesnika
Title (english)Benefits and risks from using supplements in cancer patients
AuthorMia Bašić
MentorDiana Gujinović (mentor)
Committee memberIvana Mudnić (predsjednik povjerenstva)
Committee memberJosipa Bukić (član povjerenstva)
Committee memberDiana Gujinović (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2023-10-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract
Cilj istraživanja: s obzirom na nedostatak znanja o suplementaciji onkoloških bolesnika, a koji često posežu za „prirodnijim“ pripravcima u ljekarni, cilj ovoga rada prikazati je najnovije dokaze o potencijalnim benefitima i sigurnosti primjene pojedinih dodataka prehrani u bolesnika koji se liječe od različitih malignih bolesti. Metode: elektronska bibliografska baza podataka PubMed pregledana je u ožujku i srpnju 2023. godine; jednom koristeći općenite ključne riječi iz MeSH rječnika, a... More drugi put koristeći nazive različitih suplemenata od interesa za koje postoje podatci o učestalosti primjene u ovakvih bolesnika ili već neki objavljeni relevantni rezultati. Pretraga je ograničena na petogodišnje razdoblje (2018.-2023.). Uključeni su isključivo radovi na ljudskim ispitanicima, neovisno o ustroju istraživanja. Kriteriji isključenja, između ostalog, odnosili su se na istraživanja odabrane suplementacije i prevencije nastanka raka. Rezultati: primjena dodataka prehrani može biti povezana s pozitivnim ishodima u liječenju raka kroz jačanje učinka antitumorske terapije, odgađanje pojavnosti remisije ili smanjenje štetnih učinaka osnovne terapije, čime se osigurava i njezina veća podnošljivost. Dodatci prehrani koji bi mogli imati potencijalnu korist u onkoloških bolesnika, a prikazani su u ovome radu jesu redom beta-glukan, arabinoksilan, kvercetin, rutin, luteolin, kurkumin, berberin, epigalokatehin, graviola, beta-karoten, likopen, astaksantin, vitamin D te probiotici. Zaključak: kako bi službene preporuke jednom stupile u praksu, potrebno je još studija o koristima i rizicima primjene dodataka prehrani u onkoloških bolesnika, visoke kvalitete provedbe, kao i općenito standardiziranje korisnih pripravaka u smislu određivanja pravilne formulacije i doziranja te prepoznavanja svih indikacija za koje su primjenjivi. Less
Abstract (english)
Objective: taking into account the knowledge gap on dietary supplement use in cancer patients, who often reach for more "natural" preparations in pharmacies, the aim of this study was to present the latest evidence on the potential benefits and safety profile of particular dietary supplements in patients being treated for various malignant diseases. Methods: the electronic bibliographic database PubMed was reviewed in March and July 2023; first using general keywords from the MeSH... More thesaurus, and the other time using the names of different supplements of interest for which there is data on the frequency of use in such patients, or previously published relevant findings. The search was limited to a five-year period (2018- 2023). Only articles reporting studies on human subjects were included regardless of the study design. Among the exclusion criteria were studies focused on supplementation and cancer prevention. Results: the use of dietary supplements can be associated with positive outcomes in cancer treatment by improving standard therapy, delaying remission, or reducing adverse effects of therapy, thus ensuring its better tolerability. Dietary supplements presented in this work from which cancer patients could potentially benefit are the following: beta-glucan, arabinoxylan, quercetin, rutin, luteolin, curcumin, berberine, epigallocatechin, graviola, beta-carotene, lycopene, astaxanthin, vitamin D and probiotics. Conclusion: in order for the official recommendations to be put into practice, more high-quality studies on the benefits and risks of using dietary supplements in oncology patients are needed, as well as standardization of useful products in terms of correct formulation and dosage, and recognition of all indications for which they could be applicable. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:171280
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-11-03 13:44:38
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