| Abstract | Ciljevi: Cilj ovog istraživanja bio je utvrditi mineralnu gustoću kosti u pacijenata oboljelih od
PTSP-a. Daljnji cilj istraživanja bio je analizirati antropometrijska obilježja, prisustvo šećerne
bolesti, navike i vrijednosti serumskog testosterona, vitamina D i kortizola u pacijenata sa
PTSP-om koji imaju manju mineralnu gustoću kosti u odnosu na pacijenate sa PTSP-om koji
imaju veću mineralnu gustoću kosti.
Materijali i metode: U istraživanje je uključeno 30 veterana Domovinskog rata koji boluju od
PTSP-a te se liječe kroz Program oporavka od traume. Ispitanici su podijeljeni u dvije skupine po
15 bolesnika, s obzirom na višu, odnosno nižu T- vrijednost. Za potrebe istraživanja, ispitanici su
podvrgnuti denzitometrijskom snimanju i laboratorijskim testovima.
Rezultati: Srednja T-vrijednosti za područje lumbalne kralježnice je bila -1,4, a prosječna
vrijednost TBS-a u području lumbalne kralježnice je bila 1,365. Skupina ispitanika s većom
mineralnom gustoćom kosti prema srednjoj T vrijednosti imala je značajno veću prosječnu
tjelesnu masu (P=0,04) u odnosu na skupinu ispitanika koji imaju manju T vrijednosti. Nije
bilo značajne razlike u unosu neprimjerenih količina alkohola (P = 0,203), pušenju (P = 0,719) i
učestalosti šećerne bolesti (P = 1,000) između skupine ispitanika s PTSP-om te nižom i višom Tvrijednošću.
Skupine ispitanika s PTSP-om s nižom i višom T-vrijednošću nisu se statistički
značajno razlikovale u serumskoj koncentraciji vitamina D (P = 1,000), ukupnog testosterona (P
= 0,600), slobodnog testosterona (P = 0,299) te kortizola (P = 0,254).
Zaključak: Ispitanici s PTSP-om imaju nisku mineralnu gustoću kosti
i narušenu mikroarhikteturu kosti. Između skupina ispitanika s PTSP-om i nižom i višom Tvrijednošću
nije bilo značajne razlike u unosu neprimjerenih količina alkohola,
pušenju, učestalosti šećerne bolesti, te serumskih vrijednosti testosterona, kortizola i vitamina D. |
| Abstract (english) | Objectives: The aim of this study was to determine bone mineral density in patients with PTSD.
The further aim of the study was to analyze anthropometric characteristics, presence of diabetes,
habits and values of serum testosterone, vitamin D and cortisol in patients with PTSD who have
lower bone mineral density compared to patients with PTSD who have higher bone mineral
density.
Subjects and methods: The study included 30 veterans of the Croatian War of Independence who
suffer from PTSD and are being treated through the Trauma Recovery Program. The examinees
were divided into two groups of 15 patients each, due to the higher and lower T-value. For the
purposes of the research, the examinees were exposed to densitometric imaging and laboratory
tests.
Results: The mean T-score for the lumbar spine region was -1.4 and the mean TBS value in the
lumbar spine region was 1.365. The group of examinees with higher bone mineral density
according to the mean T-score had a significantly higher average body mass (P = 0.04) compared
to the group of examinees with a lower T-score. There was no significant difference in the intake
of inappropriate amounts of alcohol (P = 0.203), smoking (P = 0.719), and the frequency of
diabetes (P = 1.000) between the group of examinees with PTSD with lower and higher T-score.
Groups of subjects with PTSD with lower and higher T-score did not show statistically significant
differences in the serum concentrations of vitamin D (P = 1.000), total testosterone (P = 0.600),
free testosterone (P = 0.299) and cortisol (P = 0.254).
Conclusion: Subjects with PTSD have low bone mineral density and impaired bone
microarchitecture. Between the groups of examinees with PTSD with lower and higher T-score,
there was no significant difference in intake of inappropriate amounts of alcohol, smoking,
incidence of diabetes, and serum values of testosterone, cortisol and vitamin D. |
