| Abstract | Cilj istraživanja: Cilj istraživanja je utvrditi povezanost između prosječnog trajanja spavanja i pojedinih kliničkih fenotipova s obzirom na ITM i metabolički status (metabolički zdravi normalne tjelesne mase, metabolički zdravi prekomjerne tjelesne mase, metabolički zdravi pretili, metabolički nezdravi normalne tjelesne mase, metabolički nezdravi prekomjerne tjelesne mase, metabolički nezdravi pretili).
Materijali i metode: Presječnim istraživanjem obuhvaćeno je 3515 ispitanika koji su podijeljeni u tri skupine, s obzirom na vrijeme prikupljanja uzorka. Prva skupina ispitanika dolazi s otoka Korčule (uzorkovanje je provedeno od ožujka do studenog 2007. godine; n=859, 24,4%), druga skupina iz grada Splita (uzorkovanje je provedeno od listopada 2008. godine do ožujka 2009. godine; n=1002, 28,5%), dok je treća skupina ispitanika također s otoka Korčule (uzorkovanje je provedeno u nekoliko navrata tijekom 2012. i 2013. godine; n=1654, 47,1%). Definicija metaboličkog sindroma, odnosno metaboličkog zdravlja postavljena je uz pomoć Joint Interim Statement definicije. Ispitanici su s obzirom na prosječno trajanje spavanja podijeljeni u tri skupine: one koji spavaju manje od 7 sati, oni koji spavaju između 7 i 9 sati i oni koji spavaju ≥9 sati na dan. U analizu su uključeni dob, spol, mjesto gdje ispitanici žive, razina obrazovanja, i ponašajni čimbenici rizika: pušenje, način prehrane i tjelesna aktivnost. U analizi podataka korišten je χ2 test, Kruskal-Wallis test i Spearmanov test rang korelacije. Razina statističke značajnosti postavljena je na P<0,05.
Rezultati: Prevalencija metaboličkog sindroma u ispitanom uzorku iznosila je 41,4%. Prevalencija metaboličkog sindroma rasla je s ITM-om. Nije nađena povezanost trajanja spavanja s učestalošću metaboličkog sindroma, osim za opseg struka. Duljina trajanja spavanja bila je statistički značajna samo za klinički fenotip metabolički zdravih i nezdravih osoba prekomjerne tjelesne mase. Metabolički zdrave osobe prekomjerne tjelesne mase su najčešće imale kratko trajanje spavanja (<7 sati), dok su metabolički nezdrave osobe s prekomjernom tjelesnom masom najčešće imale dugo trajanje spavanja (≥9 sati), što nije u skladu s rezultatima drugih istraživanja.
Zaključak: Potrebna su daljnja istraživanja za utvrđivanje prevalencije metaboličkog sindroma u Hrvatskoj, kao i prospektivno praćenje ispitanika koji su se uključili u ovo istraživanje. Na taj način će se u budućnosti moći istražiti uzročna povezanost između prosječnog trajanja spavanja i poremećaja metaboličkog zdravlja. |
| Abstract (english) | Objective: The main aim of the thesis was to establish the correlation between average sleep duration and clinical phenotypes, regarding BMI and metabolic status (metabolically healthy normal weight; metabolically healthy overweight; metabolically healthy obese; metabolically unhealthy normal weight; metabolically unhealthy overweight; metabolically unhealthy obese)
Method: Research was conducted as cross-sectional study that included a total of 3515 participants from Split and Korčula. They were divided into three groups. The first group was based on individuals from Korčula (data was collected from March to November 2007; n=859, 24.4%), second group on individuals from Split (data was collected from November 2008. to March 2009; n=1002, 28.5%), while the third group was also from Korčula (data was collected during 2012. and 2013; n=1654, 47.1%). Metabolic syndrome and metabolically healthy status were defined using Joint Interim Statement definition. Participants were divided into 3 groups regarding average sleep duration (<7 h, 7-9 h, ≥9 h). In the analysis we included age, sex, place where they live, education, and behavioral risk factors, such as smoking status, diet and physical activity. The statistical tests used were χ2 test, Kruskal-Wallis test and Spearman's rank correlation test. Level of statistical significance was set at P<0.05.
Results: The prevalence of metabolic syndrome in the studied sample was 41.4%. The prevalence of metabolic syndrome increased with BMI. The expected correlation between sleep duration and metabolic syndrome has not been confirmed, except for waist circumference. Sleep duration was statistically significant only for the clinical phenotype of metabolically healthy overweight and metabolically unhealthy overweight individuals. Metabolically healthy overweight individuals most frequently had short sleep duration (<7 h), while metabolically unhealthy overweight individuals commonly had long sleep duration (≥9 h).
Conclusion: Further studies are needed to establish the prevalence of metabolic syndrome in Croatia, as well as a prospective following of participants from this study. The latter would allow establishing a causal correlation between sleep duration and metabolic disorders. |
