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master's thesis
Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi
2020. urn:nbn:hr:171:978954
Sršen, Miro
University of Split
School of Medicine

Cite this document

Sršen, M. (2020). Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:978954

Sršen, Miro. "Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi." Master's thesis, University of Split, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:171:978954

Sršen, Miro. "Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi." Master's thesis, University of Split, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:171:978954

Sršen, M. (2020). 'Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi', Master's thesis, University of Split, School of Medicine, accessed 18 November 2024, https://urn.nsk.hr/urn:nbn:hr:171:978954

Sršen M. Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi [Master's thesis]. Split: University of Split, School of Medicine; 2020 [cited 2024 November 18] Available at: https://urn.nsk.hr/urn:nbn:hr:171:978954

M. Sršen, "Mineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi", Master's thesis, University of Split, School of Medicine, Split, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:171:978954

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Metadata
TitleMineralna gustoća kosti i trabekularna struktura kosti u bolesnika na hemodijalizi
Title (english)Bone mineral density and trabecular bone structure in patients on hemodialysis
AuthorMiro Sršen
MentorTina Tičinović Kurir (mentor)
Committee memberMladen Krnić (predsjednik povjerenstva)
Committee memberAnela Novak (član povjerenstva)
Committee memberJoško Božić (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2020, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Svrha istraživanja: Svrha ovog istraživanja bila je ispitati mineralnu gustoću kosti i trabekularnu strukturu kosti u bolesnika na hemodijalizi. Ispitanici i metode: U ovo presječno istraživanje uključena su 32 ispitanika sa završnim stadijem kroničnog bubrežnog zatajenja koji se liječe hemodijalizom na Zavodu za nefrologiju Kliničkog bolničkog centra u Splitu. Za prikupljanje podataka o ispitanicima korištena je medicinska dokumentacija iz koje su uzeti podatci o trajanju bolesti, laboratorijski nalazi, nalazi denzitometrije i vrijednosti indeksa trabekularne strukture. Ispitanici su podijeljeni u dvije skupine ovisno o duljini trajanja kronične bubrežne bolesti i duljini trajanja hemodijalize. Rezultati: Ispitanici sa završnim stadijem kroničnog bubrežnog zatajenja na hemodijalizi imaju nisku mineralnu gustoću kosti i poremećenu trabekularnu strukturu kosti. Ispitanici koji su bolovali od kronične bubrežne bolesti dulje od deset godina imali su statistički značajno nižu T vrijednosti lumbalne kralježnice (P=0,049), T vrijednosti ukupnog kuka (p=0,008), T vrijednosti vrata femura (P=0,006) i TBS-a (P=0,040) u usporedbi s ispitanicima koji su bolovali kraće od deset godina. S obzirom na duljinu trajanja hemodijalize, ispitanici koji su bili liječeni hemodijalizom dulje od pet godina imali su statistički značajno nižu T vrijednost lumbalne kralježnice (P=0,01), T vrijednost ukupnog kuka (P=0,045), T vrijednost vrata femura (P=0,020) i TBS-a (P=0,040) u usporedbi s ispitanicima koji su liječeni hemodijalizom kraće od pet godina. Zaključak: Bolesnici s duljim trajanjem kronične bubrežne bolesti i hemodijalize imaju lošiju mineralnu gustoću kosti i trabekularnu strukturu kosti.
Abstract (english)
Objectives: The purpose of this study was to examine bone mineral density and bone trabecular structure in hemodialysis patients. Materials and methods: This cross-sectional study included 32 patients with end-stage chronic renal failure treated with hemodialysis at Department of Nephrology of University Hospital of Split. Medical documentation was used to collect personal data of the participants, duration of the disease, therapy, laboratory findings, densitometry findings and TBS values. Participants were divided into two groups depending on the duration of chronic kidney disease and the duration of hemodialysis. Results: Participants with chronic kidney disease on hemodialysis have low BMD and TBS. Participants with chronic kidney disease for more than ten years had statistically significantly lower lumbar spine T values (P=0.049), total hip T values (P=0.008), femoral neck T values (P=0.006) and Trabecular bone score (P=0.040) compared to the participants who had been ill for less than ten years. Considering the duration of hemodialysis, participants who were on hemodialysis for more than five years had a statistically significantly lower T value of the lumbar spine (P=0.010), T value of the total hip (P= 0.045), T value of the femoral neck (P=0.020) and TBS (P=0.040) compared to the participants on hemodialysis for less than five years. Conclusion: Patients with a longer duration of chronic kidney disease and hemodialysis have lower bone mineral density and trabecular bone score.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:978954
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-07-17 12:46:09