Objectives: To assess the impact of dental aesthetics on students’ everyday life at the University of Split, and to determine the difference in the influence of dental aesthetics in students’ day-to-day life based on the different faculties of the students, their differing years of study, and their gender. Materials and methods: 1,300 students, ranging from the first to the sixth year of study at the University of Split, participated in the research. The PIDAQ questionnaire was used to determine the psychosocial impact of dental aesthetics on the daily lives of students at the University of Split. It is supplemented by questions of previous orthodontic treatment, their satisfaction with the results, and the person’s need for orthodontic treatment. Results: 960 (73.8%) of the participants were female, and 340 (26.2%) were male. Most of the participants are students of the Faculty of Medicine (29,4) and the third-year students prevailed (22,7%). There was a statistically significant difference between faculties while gender and year of study showed low, but still statistically significant impact on most of the asked questions. There is a great satisfaction of students with their dental aesthetics (more than 90%), men slightly more than women. The rationale for the students’ high degrees of satisfaction with their dental aesthetics is probably the fact that 50% of students have undergone some kind of orthodontic treatment. Conclusions: More than 90% of participants showed great satisfaction with their dental aesthetics, while gender and study year showed weak, but statistically significant difference between different PIDAQ questions.