Objectives: The main goal of this study is to investigate the relationship between obstructive sleep apnea and psychomotor abilities assessed with a reactionometer. Subjects and procedures: 118 subjects participated in this research, of which 102 were men and 16 were women (average age 58 years). Respondents solved three CRD tests from the simplest to the most complex. The CRD 311 test measured the speed of perception to a visual stimulus, the CRD 411 test measured the speed of complex psychomotor coordination of the limbs, and the CRD 11 test measured the speed of solving simple arithmetic operations. Discrimination of the position of a simple light signal was evaluated using the CRD 311 test. The total solution time (UKT), minimum time (MinT) and average solution time (MedT) were analyzed from the test results. Results: There are no significant differences in the speed of solving tests between different categories of daytime sleepiness according to the ESS scale. The speed of distinguishing the position of the signal did not differ significantly between subjects with a result on the PSQI scale greater than 9.5 compared to subjects whose PSQI was less than 9.5 (P=0.304), as well as in the speed of complex psychomotor reactions (P=0.343) and quick problem solving (P=0.323). Greater sleep efficiency was associated with faster problem-solving time on the test (CRD 11; r = - 0.29). There was a significant correlation between a longer time after the first falling asleep and a slower time to solve the problem of the test (CRD 11; r = 0.26 for UKT, r = 0.27 for MinT and r = 0.29 for MedT). Conclusions: Patients with OSA have disturbed sleep architecture in such a way that they have a reduced proportion of stage 3 and REM sleep stages and an increased proportion of stage 2, and this reduction is associated with slower psychomotor performance. Daytime sleepiness assessed by ESS and PSQI questionnaire is not related to deterioration of psychomotor performance of patients with OSA.