Paginacija
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Assessment of adverse drug reaction reports : metformin and metformin fixed drug combinations
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Ina Larsen Matić Objectives: The aim of the present study was to compare adverse drug reaction reports of metformin and metformin in fixed combination in Croatia from 2007 to 2018.
Materials and Methods: The data of adverse drug reaction reports received from 1 January 2007 to 31 December 2018 was analyzed in this retrospective study. Metformin reports were categorized into two main groups: single‐drug formulations and fixed‐dose combinations of drugs. The data of the year of the adverse drug...
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Assessment of nutritional status and nutritional habits in patients on hemodialysis
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Lars Brake Objectives: CKD is a pathological condition characterized by a progressive decline of renal function. It frequently results in ESRD which will require HD. The aim of this study was to assess nutritional status and adherence to Mediterranean diet in patients on hemodialysis treatment.
Materials and methods: The study included the 55 patients on HD treatment for at least 6 months that were older than 18 years. Venous blood samples were taken for evaluation of laboratory parameters. All...
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Assessment of nutritional status and quality of life in patients with percutaneous endoscopic gastrostomy
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Borna Lojpur Objectives : The main objectives of this study were to assess nutritional status and quality of life of patients who are enterally feeding via percutaneous endoscopic gastrostomy for a period of at least 3 months in the home environment.
Materials and methods: This study included a total of 31 participants, aged between 21 and 85 years, who have been feeding via percutaneous endoscopic gastrostomy for a period of at least 3 months in the home environment. Quality of life was assessed by...
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Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union
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Lydia Sekulovski Objectives: To analyze the association of European Union funding for pediatric cancer
research on pediatric cancer burden in the European Union.
Methods: EU grants awarded for childhood cancer research between January 1, 2011 and
December 31, 2019 were selected from CORDIS using MeSH-derived terms and then
categorized based on the six cancer categories (leukemia, brain/CNS, Hodgkin lymphoma,
non-Hodgkin lymphoma, kidney, and other malignancies). The IHME database was used to
derive...
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Atopija i bronhalna hiperreaktivnost kao rizični čimbenici za dijagnozu astme
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Ana-Marija Buljan CILJ ISTRAŽIVANJA:
Ispitati povezanost atopije i bronhalne hiperreaktivnosti (BHR) s dijagnozom astme u populaciji bolesnika u kojih su prisutni simptomi koji upućuju na astmu bez opstruktivnih smetnji ventilacije. Ispitati u kolikoj su mjeri atopija i bronhalna hiperreaktivnost rizični (prediktivni) čimbenici u dijagnostici astme u skupini bolesnika koji imaju simptome koji upućuju na moguću astmu a dijagnoza im nije potvrđena.
USTROJ ISTRAŽIVANJA:
Provedena je prospektivna...
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BRCA mutacije kod karcinoma jajnika - iskustva KBC Split
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Natko Čović CILJ ISTRAŽIVANJA: Mutacije BRCA1 i BRCA2 gena su poznati čimbenici rizika za
nastanak raka dojke i jajnika. Spektar BRCA1/2 mutacija u bolesnica sa seroznim karcinomom
jajnika visokog gradusa u Hrvatskoj još nije opisan. Ovakve izvješća su važna za optimizaciju
genetskog testiranja, strategiju primarne i sekundarne prevencije te za individualizaciju
liječenja naših pacijenata s rakom jajnika.
ISPITANICE I METODE: Retrospektivno su analizirani podaci iz povijesti bolesti...
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Bezreceptni lijekovi izvan ljekarne : regulatorni pregled
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Marija Pelaić Cilj istraživanja: Cilj ovog istraživanja je napraviti regulatorni pregled izdavanja bezreceptnih lijekova izvan ljekarni u zemljama Europske unije i Ujedinjenoj Kraljevini.
Materijal i metode: Sastavljen je pregled regulatornih sustava bezreceptnih lijekova u europskim zemljama, s naglaskom na dostupnost bezreceptnih lijekova izvan ljekarni. Pregledani su regulatorni zahtjevi 24 zemlje EU i Ujedinjene Kraljevine i napravljena je usporedba regulatornih sustava zemalja obuhvaćenih...
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Biljni ekstrakti kao inhibitori kolinesteraza
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Petra Jurić Cilj ovog rada je istražiti sposobnosti različitih ekstrakata i čistih spojeva koji dolaze kao sastavnice ekstrakata u inhibiciji dvaju enzima važnih u patogenezi Alzheimerove bolesti; acetilkolinesteraze (AChE) i butirilkolinesteraze (BChE). Predmet istraživanja su bili fenolni spojevi, prvenstveno flavonoidi. S ovim ciljem, pretražene su znanstvene baze podataka (ScienceDirect, Web of Science, PubMed, Google Scholar, PMC i PubChem). AChE i BChE imaju važnu ulogu u hidroliziranju...
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