Objectives: The aim of this study was to determine the prevalence of smoking, attitudes and knowledge among students of the three study programs of the University of Split Medical School, medicine, dental medicine and pharmacy regarding the impact of smoking tobacco products on oral health. The specific objectives of this study were to determine whether there is difference in knowledge, attitudes and habits between students of the third to last year in relation to gender, study program and year of study. Efforts were also made to determine whether there is a need for additional education of medical, dental and pharmacy student on the impact of tobacco on oral health. Materials and Methods: From the end of May to the beginnig of August 2020, a crosssectional study was conducted with the aim of determining the habits, knowledge and attitudes of students of the University of Split Medical School on the impact of smoking on oral health. The research was based on an online questionnaire via Google forms (Attachment) and it has been approved by the Ethics Committee of the Medical School in Split. A total of 313 students participated and the questionnaire contained three parts. In the first part of the questionnare, which consisted of 15 questions, general data and data related to the experience of cigarette smoking were collected. The second and third part of the questionnaire were focused on attitudes and knowledge about the impact of smoking on oral health. Results: When it comes to the prevalence of smoking tobacco products, 31,9 % of students have never tried smoking, and the prevalence of smokers and occasional smokers is 27,7 %. The majority of smokers were pharmacy students (32,2 %) and largest percentage of them (30,3 %) started smoking between the ages of 15 and 18. Compared to medical and pharmacy students, dental students showed more knowledge about the impact of smoking tobacco products on oral mucosal health. Students of pharmacy (50,5 %) consider that they have least necessary knowledge for advising patients on smoking cessation and 87,1 % of all students expressed a desire for better education. Almost 69,9 % of all students believe that dentists who smoke less often advise patients to quit smoking and 31,4 % of students stated that they will lose a patient by counseling about smoking cessation. Conclusion: In this study we have shown that there is no statistically significant influence of gender, year of study and study program towards the habits of the students. Dental students and senior students of all three studies have shown better knowledge of the effect of tobacco products on oral health. However, poorer knowledge was shown by pharmacy students. Students of all three studies showed a desire for better education on the topic of counseling patients to quit smoking.