Objectives: The aim of this study was to review the regulatory framework medicinal cannabis at a global level. Material and methods: An overview of existing regulations for medical cannabis products in the EU, USA, Canada, Japan, Australia and New Zealand was made. Legal regulations and legal texts that define the status of medical cannabis in a particular country are analyzed. The focus of the search for medical cannabis regulations was on medicinal products with a marketing authorization, the method of obtaining an authorization for the use of medical cannabis, approved indications, the method of prescribing certain country-specific characteristics. Results: Medical cannabis is the subject of discussion and research all over the world. A division of cannabis-based products into those with a marketing authorization and those without authorization was observed. The approved medicinal product means the patient wil get a product with a high degree of control and safety established by clinical and non-clinical trials. Regulatory agencies in the EU, Canada, the US, Australia and New Zealand have approved several medical cannabis-based drugs for specific indications. In Japan, a strict law is still in place that prohibits any use of cannabis for medical and non-medical purposes. In most countries, a regulatory framework has been established for the cultivation of medical and non-medical cannabis, and a percentage of THC that divides these categories has been defined. Common to all processed countries, except Japan, which is still considering the introduction of medical cannabis, is the trend of liberalization and increasing market saturation of all cannabis-based products - from food products without THC to approved drugs for well-defined indications. Conclusion: Laws regulating medical cannabis vary depending on the continent, the state, and even the province within the state. Different control models need to be examined and a unique conclusion drawn about the future of medical cannabis. Additional research on the pharmacodynamics and pharmacokinetics of cannabinoids itself will certainly contribute to a safer regulatory framework that protects the patient, but also the prescriber of medical cannabis.