Objectives: The aim of this study is to present microbiological and epidemiological characteristics of candidiasis in outpatient population of Split-Dalmatia County during a period of 10 years (2012. – 2021.). Materials and methods: This retrospective study was conducted using data from the archives of the Public Health Institute of Split-Dalmatia County in the ten-year period from 1. 1. 2012. to 31. 12. 2021. The data on the type of isolated fungi, patients age and gender, type of sample, as well as the date of sample collection were analyzed. Results: In the observed period a total of 9083 Candida isolates were isolated at the Public Health Institute of Split-Dalmatia County, most often from oral swabs (33.06%), tongue swabs (21.94%) and stool samples (16.59%). C. albicans was the most common isolate (70.1%), while the most frequently isolated non-albicans species was C. glabrata (13.23%), followed by C. parapsilosis (4.1%), C. krusei (2.84%) and C. tropicalis (2.09%). Other Candida species were isolated in less than 1% of cases. Candida infection, regardless of the species, is more common in women (74.52%). C. glabrata, C. tropicalis and C. kefyr were more often isolated in females, while C. lusitaniae, C. famata and C. parapsilosis were more common among males. The median age of patients in whom non-albicans species were isolated was 4 years higher than the age of patients in whom C. albicans was isolated. In the observed period, there was a statistically significant increase in the number of C. parapsilosis isolates, while a decrease in the number of C. famata and unidentified isolates was observed. The occurrence of Candida, regardless of the species, is higher in autumn. Conclusions: The results presented in this study, according to the data from the world literature, show that C. albicans is still the leading causative agent of candidiasis. The frequency of nonalbicans species which are more resistant to antifungals is of great concern. C. glabrata and C. krusei are the second and fourth most frequent Candida isolates in the outpatient population. A statistically significant increase in the number of C. parapsilosis isolates was found. Further monitoring of the local epidemiological situation regarding the causative agents of candidiasis is important.