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master's thesis
HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA
2017. urn:nbn:hr:171:275705
Ćurčija, Matea
University of Split
School of Medicine
Oral medicine and parodonthology

Cite this document

Ćurčija, M. (2017). HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA (Master's thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:275705

Ćurčija, Matea. "HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA." Master's thesis, University of Split, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:171:275705

Ćurčija, Matea. "HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA." Master's thesis, University of Split, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:171:275705

Ćurčija, M. (2017). 'HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA', Master's thesis, University of Split, School of Medicine, accessed 02 May 2022, https://urn.nsk.hr/urn:nbn:hr:171:275705

Ćurčija M. HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA [Master's thesis]. Split: University of Split, School of Medicine; 2017 [cited 2022 May 02] Available at: https://urn.nsk.hr/urn:nbn:hr:171:275705

M. Ćurčija, "HUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA", Master's thesis, University of Split, School of Medicine, Split, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:171:275705

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Metadata
TitleHUMORALNA IMUNOST U OSOBA OBOLJELIH OD ORALNOG LIHEN RUBERA
Title (english)HUMORAL IMMUNITY IN PATIENTS WITH ORAL LICHEN RUBER
AuthorMatea Ćurčija
MentorDolores Biočina-Lukenda (mentor)
GranterUniversity of Split
School of Medicine
(Oral medicine and parodonthology)
Split
Defense date and country2017, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Medicine
Abstract
Oralni lihen ruber je kronična mukokutana autoimuna bolest nerazjašnjene etiologije. Smatra se da alteracija keratinocita stimulira početak imunoreakcije ili imunoreakcija dovodi do preobrazbe keratinocita. Cilj ovog istraživanja je bio utvrditi stanje humoralne imunosti kod oboljelih od OLR-a. U ispitivanju je sudjelovalo 30 osoba oboljelih od OLR-a i 30 zdravih osoba kao kontrolna skupina. Humoralna imunost određena je utvrđivanjem vrijednosti IgG, IgM i IgA u serumu. Rezultati su pokazali značajno povišenje razine IgA i IgM u pacijenata s OLR-om, te neznačajno povišene razine IgG. To govori o sistemnoj imunoreakciji kod oboljelih i moglo bi pomoći u razumijevanju patogeneze ove bolesti.
Abstract (english)
Oral lichen ruber (OLR) is a chronic mucocutaneous autoimmune disease with unknown etiology. Either alteration of keratinocytes stimulates the beginning of the immunological reaction or keratinicyte changes are result of a immunological reaction. The aim of this study was to investigate humoral immunity of patients with OLR. The study sample consisted of 30 patients with OLR and 30 healthy participants who were serving as control group. Humoral immunity was determined with concentration of immunoglobulins IgG, IgA and IgM in serum. Results showed significantly elevated values of IgA and IgM in serum of patients with OLR and unsignificantly elevated value of IgG. Results showed that sistemic immunoreactin was present in patients with OLR and it could help understanding pathogenesis of this disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:275705
Study programmeTitle: Dental Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-02-15 08:55:46