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The effects of long-term diabetes mellitus on adult neurogenesis in subventricular zone of the rat brain
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Tim Hendrik Boy Objectives: Diabetes mellitus has been associated with increased risk of cognitive decline, dementia, depression and anxiety. The aims of this study were to determine the influence of aging and long-term type 1 diabetes mellitus (DM1) on the rate of adult neurogenesis in subventricular zone of rats, as well as to determine the possible role of DSTYK protein in the adult neurogenesis in subventricular zone of rats as a possible disease mechanism.
Material and Methods: Thirty-five male...
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The effects of moderate daily red wine intake on arterial stiffness and hemodynamic parameters in type 2 diabetes mellitus
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Anika Katarina Januš Introduction: Type 2 Diabetes Mellitus (T2DM) is a prevalent cause of morbidity and mortality, particularly due to chronic complications development, most commonly cardiovascular diseases. Among markers for assessment of clinical and subclinical signs of cardiovascular disease, the presence of arteriosclerosis, and stiffening of arterial walls as indicated by the arterial stiffness, was proven to be an important predictor of adverse cardiovascular events. Carotid-femoral pulse wave velocity...
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The expression of Pannexin 1 in the developing human spinal cord and dorsal root ganglia
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Julia Christina Zeitler Objectives: The objective of this study was to explore the expression of Pannexin 1 (Panx1) in
the spinal cord (SC) and ganglia of human conceptus during early phase of intrauterine
development.
Material and methods: The human conceptus tissue was collected from the Department of
Gynecology and Obstetrics and the Department of Pathology after tubal pregnancies or after
spontaneous abortions. The immunohistochemistry procedure was used to visualize the targeted
proteins. The data...
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The expression pattern of Notch2 and Dab1 in the postnatal kidney of Dab1-/- mice
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Larissa Gudelj Ensor Objectives: The expression and localization of Dab1 adaptor proteins and Notch2 receptors in the nephrons of yotari (Dab1 -/-), heterozygote (Dab1 +/-), and Wildtype (Dab1 +/+) mice was analyzed to further develop their suggested importance in mammal kidneys overall, but also their significance particularly in yotari mice nephrons.
Materials and methods: yotari, heterozygote and wildtype mice were sacrificed on the 4th postnatal day. Paraffin embedded kidney tissue sections were analyzed...
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The impact of double standards and openness to redefine stigma in sexual relationships of medical students
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Marino Lukenda Sexual health, per the WHO, includes physical, emotional, mental, and social aspects of sexuality. It stresses a positive and respectful approach to sexual relationships and rights. However, public health often emphasizes the negative outcomes and risks, neglecting the important aspects of sexual well-being and pleasure. Integrating these aspects into public health is crucial for addressing inequalities and improving overall sexual health and justice.
OBJECTIVES:
This research explores how...
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The impact of the COVID-19 pandemic on the outcome of myocardial infarctions
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Tom Witthauer Objectives: The objective of this study was to examine whether the social, political, and medical changes during the corona virus disease 2019 (COVID-19) pandemic had a significant impact on the outcome of myocardial infarctions.
Materials and Methods: The study was designed as a retrospective analytical cross-sectional study. Data was acquired from the REGIOMED hospital in Coburg, Germany. 999 data sets of patients were used. In the time frame from the 2nd of March 2020 and the 28th of...
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