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Citotoksično djelovanje tienopiridinskih derivata na stanice humanog karcinoma jajnika
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Andrea Braica Cilj istraživanja:
Cilj ovog istraživanja utvrditi je potencijalno citotoksično djelovanje derivata tieno[2,3-b]piridina na staničnoj liniji humanog karcinoma jajnika.
Materijali i metode:
Citotoksičnost spojeva tieno[2,3-b]piridina, odnosno inhibitora 5, 6, 8 i 9 ispitivana je na SKOV-3 staničnoj liniji korištenjem MTT metode na temelju koje se određuje postotak metabolički aktivnih stanica. Učinak tieno[2,3-b]piridina ispitivan je u sedam različitih koncentracija nakon 4, 24,...
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Citotoksično djelovanje tienopiridinskog derivata na humane stanice karcinoma grlića maternice
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Maja Jelović Cilj istraživanja:
Cilj istraživanja bio je ispitati potencijalnu citotoksičnost novo-sintetiziranih tienopiridinskih derivata na humanim stanicama karcinoma grlića maternice HeLa i SiHa. Pretpostavka je da će se metabolička aktivnost stanica smanjiti nakon izlaganja derivatima u odnosu na kontrolnu skupinu.
Materijali i metode:
Citotoksičnost se ispitala MTT metodom koja određuje postotak metaboličkih aktivnih stanica nakon tretiranja tienopiridinskim derivatima (inhibitori 5,...
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Classification of stillbirths in University Hospital of Split by relevant condition at death (ReCoDe) system
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Kadir Er Objectives: to determine causes of stillbirth according to ReCoDe classification system, with emphasis on stillbirth cases classified only as "mors fetus" by clinicians.
Materials and methods: retrospective study over a time span of 7 years evaluated 115 stillbirths. The collected data included pathological data, both autopsy reports and placental pathological reports and clinical information from the autopsy request forms.
All of the stillbirth cases were allocated into one of the...
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Clinical and cytogenetic features of leukemias in children treated in the University Hospital of Split from 2000 to 2017
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Lorenz Diether Bastian Objectives: Pediatric leukemias are generally characterized by recurrent genetic aberrations, which are thought to be specifically associated with diagnosis and prognosis. The aim of the study was to investigate the frequency and types of acquired chromosomal aberrations and correlation with other biological characteristics and prognostic risk factors.
Materials and methods: We retrospectively reviewed clinical features and results of cytogenetics and molecular analysis for patients...
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Clinical and demographical features of adult patients with acute intoxication admitted to a medical intensive care unit
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Lukas Kvartuč Objectives: The objective of study was to assess the demographics, clinical parameters and outcome of acute intoxications among adult patients admitted in medical ICU (intensive care unit) in southern Croatia.
Subjects and Methods: An observational retrospective study was conducted during one-year period. Subjects were patients admitted to the ICU due to acute poisoning.
Results: 81 subjects (32.1% females) aged 43.16±14.77 years were admitted in ICU due poisoning (14.97% of total...
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Colles’ fracture treatment and rehabilitation at University Hospital of Split : one-year retrospective study
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Marina Belcovska Objectives: The purpose of this retrospective study was to establish the number, gender and age of patients that suffered a Colles’ fracture during the calendar year 2016. in Split. As well as the prevalence of conservative treatment compared to surgical treatment, and the prevalence of post-fracture rehabilitation at University Hospital of Split. Subjects and methods: Data was collected from the Surgical Emergency Department’s paper database and cross-referenced to the Institute of...
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Comparative analysis of antiglaucoma generic and original eye drugs in Split-Dalmatia County
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Viktor Marin Mastnak Aim of the thesis: The primary aim of this research in medical anti-glaucoma therapy is to find out the total number of anti-glaucoma drugs in Split-Dalmatia county in the last 5 years, especially with regards to consumption of original anti-glaucoma drugs against their generic counterparts and comparison between fixed (combined) and mono therapy. Also we want to show if the prescription of prostaglandin analogues has risen through the years.
Patients and methods: In this research we used...
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