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Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split
Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split
Anna Husebo Anso
Objectives: To examine the hormonal levels of adolescents with varicocele, specifically focusing on FSH, LH, and inhibin B, treated and followed at Department of Pediatric Surgery at University Hospital of Split. We aim to determine the prevalence of normal, high, or low levels of these hormones in the patient cohort and assess if routine hormonal tests offer any significant diagnostic or prognostic value in the management of varicocele. Materials and methods: This study was designed as...
Hormonski status štitne žlijezde u bolesnika s teškim oblikom SARS-CoV-2 infekcije
Hormonski status štitne žlijezde u bolesnika s teškim oblikom SARS-CoV-2 infekcije
Mislav Baković
Cilj istraživanja: Glavni je cilj ovog istraživanja bio je ispitati dinamiku hormonskog statusa štitnjače u bolesnika s teškim oblikom SARS-CoV-2 infekcije koji su liječeni u jedinici intenzivnog liječenja (JIL) Kliničkog bolničkog centra Split. Promatrane su vrijednosti tireotropina (TSH), slobodnog T₃ i slobodnog T₄ prvog, sedmog i četrnaestog dana od primitka u JIL-a. Ispitanici i postupci: U istraživanje je uključeno 43 muška ispitanika prosječne dobi 56,1 godina...
Host genetics in tuberculosis susceptibility
Host genetics in tuberculosis susceptibility
Alja Štefelin
Objectives: The aim of this study was to investigate the genetic background underlying increased risk of developing tuberculosis. Methods: A subset of the 10,001 Dalmatians study data were used for purpose of this study. We performed a genome-wide association analysis of the subjects who had a medical record of hospital admission due to tuberculosis. All other subjects who were not admitted to hospital for tuberculosis treatment were considered as controls. Results: A single...
Humoralna imunost u osoba oboljelih od oralnog lihen rubera
Humoralna imunost u osoba oboljelih od oralnog lihen rubera
Matea Ćurčija
Oralni lihen ruber je kronična mukokutana autoimuna bolest nerazjašnjene etiologije. Smatra se da alteracija keratinocita stimulira početak imunoreakcije ili imunoreakcija dovodi do preobrazbe keratinocita. Cilj ovog istraživanja je bio utvrditi stanje humoralne imunosti kod oboljelih od OLR-a. U ispitivanju je sudjelovalo 30 osoba oboljelih od OLR-a i 30 zdravih osoba kao kontrolna skupina. Humoralna imunost određena je utvrđivanjem vrijednosti IgG, IgM i IgA u serumu. Rezultati su...
Hyponatremia – A new diagnostic marker for complicated acute appendicitis in children: a systematic review and meta-analysis
Hyponatremia – A new diagnostic marker for complicated acute appendicitis in children: a systematic review and meta-analysis
Jana Ros Birley
Objectives: In the search for new biomarkers in the diagnosis of complicated appendicitis in children, this meta-analysis aimed to investigate all available data on hyponatremia as a marker of complicated appendicitis in the pediatric population, and compare the levels of sodium in patients with non-complicated appendicitis. Materials and Methods: A total of 4 databases were searched for relevant articles, using the the search keywords (hyponatremia) AND (appendicitis) AND...
Identifikacija i klasifikacija mikroorganizama s korištenih četkica za zube
Identifikacija i klasifikacija mikroorganizama s korištenih četkica za zube
Roko Duplančić
Uvod: Oralna je higijena praksa pojedinca u održavanju zuba i usne šupljine čistima u svrhu prevencije oralnih bolesti. Četkica za zube najrašireniji je, najprihvaćeniji i najkorišteniji instrument u održavanju oralne higijene. Svakodnevnom upotrebom na površini vlakana četkice mogu zaostati različiti mikroorganizmi. Cilj istraživanja: Identifikacija i klasifikacija mikroorganizama s korištenih četkica za zube te određivanje spadaju li oni u fiziološku mikrobiotu ljudske...
Identifying alterations at the bone-implant-interface of experimental joint replacement prostheses models by means of new ultrasonic measurement methods
Identifying alterations at the bone-implant-interface of experimental joint replacement prostheses models by means of new ultrasonic measurement methods
Antonia Friedrich
Objectives: This study aimed to evaluate the feasibility of ultrasound as a noninvasive method to characterize bone to implant alterations. Our goal was to show that ultrasonic sensors allow identification of gaps at a much smaller size than conventional radiological methods, thereby enabling early detection of loosened implanted endoprostheses. Materials and methods: First, two idealized three layer systems, a cylindrical aluminium-water-aluminium system and a planar bone-water-metal...
Immunohistochemical expression of Podoplanin and P16-INK in  Oral Squamous Cell Carcinomas
Immunohistochemical expression of Podoplanin and P16-INK in Oral Squamous Cell Carcinomas
Kerstin Er
Objectives: to determine the immunohistochemical expression of Podoplanin (PDPN) and p16- INK in oral cavity- and oropharyngeal squamous cell carcinoma (OSCC). Furthermore, we wanted to investigate the correlation between the expression of the two immunohistochemical factors and the histological characteristics of the tumor. Additional parameters analysed were the pathological stage, histological grade, age, gender, involvement of lymph node and lymphovascular- and perineural tissue. ...
Impact of atrial fibrillation on outcomes in patients undergoing transcatheter mitral valve repair
Impact of atrial fibrillation on outcomes in patients undergoing transcatheter mitral valve repair
Johann Jakob Friedrich Strohmaier
Objective: The aim of this study was to examine the impact of AF in patients with severe MR after being treated by PMVR. Material and Methods: All patients who underwent PMVR with MitraClip for severe mitral regurgitation and were enrolled between 2016 and 2021 during a 5-year period were included in the registry study. Two groups of patients were created: one with AF (group A) and the other without (group B). Following this, there was a comparison of the two groups' clinical...
Impact of interventional cardiology under the influence of COVID-19
Impact of interventional cardiology under the influence of COVID-19
Franziska Leandra Kiefer
Background: With mitral regurgitation being the most common valve disease in the industrialized world, it affects roughly 10% of elderly over the age of 75 years. Due to demographic changes, its prevalence is thought to even increase in the future. TEER, particularly the MitraClip® system, is a suitable option for patients with an increased surgical risk. This thesis addresses the question of how the strained healthcare system during the pandemic has affected cardiological patients...
Impact of left atrial fibrosis tissue before and induced scar tissue after pulmonary vein isolation on left atrial function detected using cardiac-MRI in patients with atrial fibrillation
Impact of left atrial fibrosis tissue before and induced scar tissue after pulmonary vein isolation on left atrial function detected using cardiac-MRI in patients with atrial fibrillation
Mariella Franziska Andrea Zuber
Objectives: The aim of this study is to determine the influence of atrial fibrosis before and induced scar tissue after PVI on the left atrial function in patients with paroxysmal AF. Materials and methods: 30 patients from the cardiology department of REGIOMED Hospital in Coburg, Germany, were included in this retrospective, non-invasive and non-randomized study, using data collected between June 2021 and June 2022. Inclusion criteria comprised high-quality MRI scans, sinus rhythm during...
Imunofenotipizacija u bolesnika s multiplom sklerozom liječenih okrelizumabom u KBC-u Split
Imunofenotipizacija u bolesnika s multiplom sklerozom liječenih okrelizumabom u KBC-u Split
Marija Radmilo
Cilj istraživanja: Prikazivanje i usporedba imunofenotipizacije T-limfocita, B-limfocita i NK stanica prije primjene prve i prije primjene druge doze okrelizumaba u bolesnika oboljelih od MS-e u KBC-u Split od 1. siječnja 2019. do 31. prosinca 2021. godine. Ispitanici i postupci: Uključeno je 22 pacijenata oboljelih od MS-e starijih od 18 godina koji su se liječili okrelizumabom u Klinici za neurologiju KBC-a Split u navedenom trogodišnjem razdoblju. Analizirani su podatci o spolu,...

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