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master's thesis
Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera
2023. urn:nbn:hr:171:923424
Žalac, Martina
University of Split
School of Medicine

Cite this document

Žalac, M. (2023). Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:923424

Žalac, Martina. "Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:923424

Žalac, Martina. "Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:923424

Žalac, M. (2023). 'Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera', Master's thesis, University of Split, School of Medicine, accessed 15 November 2024, https://urn.nsk.hr/urn:nbn:hr:171:923424

Žalac M. Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera [Master's thesis]. Split: University of Split, School of Medicine; 2023 [cited 2024 November 15] Available at: https://urn.nsk.hr/urn:nbn:hr:171:923424

M. Žalac, "Učestalost bolesti štitnjače u oboljelih od oralnog lichen rubera", Master's thesis, University of Split, School of Medicine, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:171:923424

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Metadata
TitleUčestalost bolesti štitnjače u oboljelih od oralnog lichen rubera
Title (english)Frequency of thyroid gland disease in patients with oral lichen ruber
AuthorMartina Žalac
MentorDolores Biočina-Lukenda (mentor)
Committee memberLivia Cigić (predsjednik povjerenstva)
Committee memberAntonija Tadin (član povjerenstva)
Committee memberIvan Galić (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2023-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Medicine
Abstract
Ciljevi: Glavni cilj ovog istraživanja bio je utvrditi učestalost bolesti štitnjače kod pacijenata sa oralnim lichen ruberom. Specifični ciljevi bili su utvrditi učestalost povišenih vrijednosti TSH, T3 i T4 te učestalost pozitivnog nalaza antiTPO i antiTg kod osoba s oralnim lichen ruberom. Materijali, metode i ustroj istraživanja: Uzete su anamneze pacijenata te su po potrebi su učinjene serološke pretrage (TSH, T3, T4, antiTPO i antiTG). Rezultati: Bolest štitnjače pronađena je kod više od polovice pacijenata s dijagnosticiranim OLR-om. Povišena serumska vrijednost TSH pronađena je kod 22,7% pacijenata. Parametar je bio povišen kod polovice slučajeva kad bolest štitnjače nije dijagnosticirana. Vrijednost T3 bila je povišena kod 18,2% pacijenata te manje od polovice (40%) onih bez dijagnosticirane bolesti štitnjače. Serumske razine T4 unutar referentnog intervala uz povišene vrijednosti TSH mogu upućivati na subklinički hipotireoidizam. Serumske vrijednosti protutijela antiTPO i antiTG bile su pozitivne kod 13,6% pacijenata. Iste su iste bile pozitivne kod 30% pacijenata koji nisu imali dijagnosticiranu bolest štitnjače. Zaključci: Bolest štitnjače pronađena je kod više od polovice pacijenata s dijagnosticiranim oralnim lichen ruberom. Povišena serumska vrijednost hormona TSH i T3 pronađena je kod dijela pacijenata s ORL-om i oko polovice istih bez prethodne dijagnoze bolesti štitnjače. Serumske razine T4 unutar referentnog intervala uz povišene vrijednosti TSH mogu upućivati na subklinički hipotireoidizam. Serumske vrijednosti protutijela antiTPO i antiTG bile su pozitivne kod manjeg broja pacijenata i oko trećine pacijenata koji nisu imali dijagnosticiranu bolest štitnjače.
Abstract (english)
Objectives: The main aim of this study was to determine the frequency of thyroid gland disease in patients with oral lichen ruber. Specific aims were to determine the frequency of elevated levels TSH, T3, T4 and the frequency of positive antibody tests for TPOAb and TgAb in patients with oral lichen ruber. Materials, methods and organization of research: Patients' anamnesis were taken and serological tests were made if needed. Results: Thyroid disease was found in more than half of patients with diagnosed oral lichen ruber. Elevated TSH serum level was found in 22,7% of patients. Parameter was raised in half cases when ORL hasn't been diagnosed. T3 level was raised in 18,2% of patients and in less then half (40%) of them without diagnosed thyroid disease. Serum levels of T4 in reference interval with elevated TSH levels can refer to subclinical hypothyroidism. TPOAb and TgAb serum levels were positive in 13,6% patients. The same were positive in 30% patients without diagnosed thyroid disease. Conclusions: Thyroid disease was found in more than half of patients with diagnosed oral lichen ruber. Elevated serum levels of TSH and T3 were found in some of the patients and half of the same without previous thyroid disease diagnosis. Serum levels of T4 in reference interval with elevated TSH levels can refer to subclinical hypothyroidism. TPOAb and TgAb serum levels were positive in a smaller number of patients and about a third of patients that were not diagnosed with thyroid disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:923424
Study programmeTitle: Dental Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-07-14 07:28:07