Objectives: The aim of this study was to assess health related quality of life and subjective feeling of health in partially or completely edentulous individuals. Materials and methods: There were 34 participants included in the study, who attended the Department of Prosthodontics in the Dental Clinic Split, Croatia for new complete dentures fabrication. Following the clinical examination, participants completed a quality of life questionnaire, the 36-Item Short Form Health Survey (SF-36), measuring subjective feeling of health through eight health domaines, oral health related quality of life questionnaire (OHIP-14) and visual-analogue scale (VAS) to assess patient satisfaction with the previous complete dentures. Results: Out of 34 participants in this study, there were 26 female (76.5%) and 8 male (23.5%), with the mean age 70.6±9.4 years. There were 18 (52.9%) completelly edentulous and 16 (47.1%) partially edentulous participants. Complete denture was previously used by 30 (88.2%) participants, partial denture by 11 (32.4%) and fixed prosthetic restorations by one (2.9%) participant. Participants previously using complete dentures estimated their satisfaction on VAS scale with 57.5±32.0 mm. Results of the health related quality of life assessed by SF-36 questionnaire showed lowest results in the Energy and vitality domaine (55.8±16.1 points), while the highest score was reached in the Mental health domaine (89.9±22.7 points). Total sum of OHIP-14 score was 17.2±12.5 points (out of maximal 56 points), with no statistically significant differences between completelly and partialy edentulous participants. Conclusion: This study showed that completelly or partialy edentulous individuals presented reduced quality of life, as well as subjective feeling of health. Therefore, oral rehabilitation including fabrication of prosthetic restorations is necessary to improve their quality of life.