prikaz prve stranice dokumenta Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split
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master's thesis
Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split
2023. urn:nbn:hr:171:576776
Anso, Anna Husebo
University of Split
School of Medicine

Cite this document

Anso, A. H. (2023). Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:576776

Anso, Anna Husebo. "Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:576776

Anso, Anna Husebo. "Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:576776

Anso, A. H. (2023). 'Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split', Master's thesis, University of Split, School of Medicine, accessed 01 April 2025, https://urn.nsk.hr/urn:nbn:hr:171:576776

Anso AH. Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split [Master's thesis]. Split: University of Split, School of Medicine; 2023 [cited 2025 April 01] Available at: https://urn.nsk.hr/urn:nbn:hr:171:576776

A. H. Anso, "Hormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split", Master's thesis, University of Split, School of Medicine, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:171:576776

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Metadata
TitleHormones FSH, LH and Inhibin B levels in adolescent treated and followed due to varicocele at pediatric surgery Split
AuthorAnna Husebo Anso
MentorDavor Todorić (mentor)
Committee memberZenon Pogorelić (predsjednik povjerenstva)
Committee memberJakov Meštrović (član povjerenstva)
Committee memberJasenka Kraljević (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2023-09-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract
Objectives: To examine the hormonal levels of adolescents with varicocele, specifically focusing on FSH, LH, and inhibin B, treated and followed at Department of Pediatric Surgery at University Hospital of Split. We aim to determine the prevalence of normal, high, or low levels of these hormones in the patient cohort and assess if routine hormonal tests offer any significant diagnostic or prognostic value in the management of varicocele. Materials and methods: This study was designed as a... More retrospective cohort study conducted at the Department of Pediatric Surgery, University Hospital of Split in Croatia. All data was collected from the hospital’s patient records between 1st of May 2015 to 1st June 2023. This cohort study included a total of 120 participants. The data collection was exclusively extracted from the Department of Pediatric Surgery at the University hospital of Split. Spanning from 2015 to 2021, included exclusively patients treated by a single surgeon. Exclusion criteria for this period involved the absence of recorded LH, FSH, or Inhibin B hormonal levels. For the period 2021 to 2023, the data was collected from the hospital’s system, including patients treated by other surgeons as well. We recorded the patient age, FSH, LH and inhibin B hormonal levels, and whether the patient had undergone surgery. Results: Majority of participants have FSH, LH and Inhibin B levels within the normal reference range. The test statistics shows that there is no significant difference in the levels of LH;(p = 0.081) between operated and non-operated patients. However, there is statistically significant evidence to conclude that the Inhibin B levels;(p = 0.008) were higher for the nonoperated (M=187, SD=77) than operated (M=119, SD=66) patients. There was no significant difference in the FSH values for operated (M=5, SD=4) and non-operated patients (M=3.7, SD=2) conditions; (p = 0.075). Conclusions: In conclusion, this study revealed no statistically significant difference between FSH and LH values in operated and non-operated adolescents. However, a statistically significant difference was found between the inhibin B values in operated and non-operated. However, those who underwent surgery were more likely to have inhibin B values in the lower half of the spectrum compared to their non-operated counterparts. The relevance of monitoring FSH and LH levels does not appear to influence the decision to proceed with varicocelectomy. Further investigations should be done to determine the importance of inhibin B levels in guiding the decision to undergo varicocelectomy. Less
Abstract (croatian)
Cilj: Ispitati razine hormona u adolescenata s varikokelom, s posebnim naglaskom na FSH, LH i inhibin B, liječenih i praćenih u Klinici za dječju kirurgiju Kliničkog Bolničkog Centra (KBC) Split. Cilj nam je bio u skupini ispitanika odrediti prevalenciju normalnih, visokih ili niskih razina ovih hormona i procijeniti imaju li rutinski hormonski testovi značajnu dijagnostičku ili prognostičku vrijednost u liječenju varikokele. Materiali i metode: Ovaj rad je osmišljen kao retrospektivno... More kohortno ispitivanje provedeno u Klinici za dječju kirurgiju KBC-a Split, Podatci su prikupljeni iz medicinske dokumentacije bolesnika liječenih u razdoblju od 1. svibnja 2015. do 1. siječnja 2023. Ispitivanjem je obuhvaćeno 120 ispitanika. Podatci prikupljeni u razdoblju od 2015. do 2021. odnose se na bolesnike liječene od strane jednog liječnika. U istraživanje su ukjljučeni samo oni bolesnici s nalazima LH, FSH i inhibina B. U razdoblju od 2021-2023 podatci su prikupljani iz bolničkog informacijskog sustava te su uključeni i bolesnici drugih liječnika s istim kriterijima. Prikupljeni su podatici o dobi bolesnika, razinama hormona FSH, LH i inhibina B te je li bolesnik podvrgnut operaciji ili ne. Resultati: Većina ispitanika je imala razine FSH, LH i inhibina B unutar referentnih vrijednosti. Statistička obrada nije pokazala statistički značajnu razliku u razinama LH (p = 0.081) između operiranih i neoperiranih bolesnika. Postoji statistička značajnost za zaključak da su razine inhibina B; (p = 0.008) bile više u neoperiranih (M=187, SD=77) od operiranih bolesnika (M=187, SD=77). Nije bilo statističke razlike u vrijednostima FSH; (p = 0.075) operiranih (M=5, SD=4) i neoperiranih bolesnika (M=3.7, SD=2). Zaključak: Istraživanje nije pokazalo ststistički značajne razlike u vrijednostima FSH i LH između operiranih i neoperiranih adolescenata. Postoji ststistički značajna razlika u vrijednostima inhibina B operiranih i neoperiranih bolesnika. Bolesnici koji su podvrgnuti operaciji će vjerojatnije imati vrijednosti inhibina B u donjem dijelu normalnog raspona vrijednosti od skupine neoperiranih bolesnika. Praćenje razina FSH i LH se nije pokazalo relevantnim u donošenju odluke o potrebi varikocelektomije. Potrebno je provesti dodatna istraživanja kako bi se utvrdila važnost razina inhibina B u odlučivanju potrebe za varikocelektomijom. Less
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:576776
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-10-20 07:42:18
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