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Comparison of suicide rates during the Covid-19 pandemic and the 10 years prior in Split-Dalmatia county
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Gabriela Chatzigeorgiou Objectives: The aim of this study was to investigate and compare suicide rates in regard to age groups, gender, place, cause of death and type of suicide, during the COVID-19 pandemic and the 10 years prior in Split-Dalmatia County, Croatia. Additionally, we aimed to investigate overall suicide incidence during pre-COVID and the COVID pandemic .
Subjects and methods: This retrospective epidemiological study included 481 subjects, which were categorized by age groups, gender, place, type of...
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Comparison of surgical treatment for pleural empyema patients - open surgery versus minimally invasive surgery
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Lea Bruhn Objectives: The aim of this study was to compare the treatment strategies of the original 500 pleural empyema patients from the REGIOMED clinics, in Germany, particularly regarding surgical management using minimally invasive surgery versus open thoracotomy. Specifically, the parameters of in-hospital mortality, postoperative stay, hospital readmission, and survival after one year were examined and compared.
Materials and Methods: Originally, 500 patient data with the diagnosis of pleural...
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Comparison of the clinical parameters of paricalcitol and finerenone in slowing down the progression of chronic kidney disease
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Delia Mellis Objective: The aim of the study was to investigate and evaluate the available data regarding the progression of CKD and extent of proteinuria in view of the association between CKD and cardiovascular outcomes and, furthermore, between the extent of proteinuria and its association with progression of CKD.
Material and Methods: PubMed was searched using the search key words (finerenone) or (paricalcitol) AND (albuminuria). All patients with CKD, DMT2 and treatment with ACEi or ARBs were...
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Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome
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Yeliz Koc Objectives: The purpose of this study was to compare acute coronary syndrome patients who
were old or very old (≥75 years) to younger patients in terms of coronary pathology,
comorbidities, coronary intervention, and the short-term outcome following PCI.
Materials and Methods: This retrospective monocentric investigation was performed between
January 1 and October 1, 2022, and included all patients who were treated invasively for their
acute coronary syndrome. Patients were...
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Correlation between diabetic retinopathy and sensory-motor neuropathy : a cohort study
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Daniel Hyun Gunderlach Objectives: The objective of this study was to provide a comprehensive insight into common pathological mechanisms of diabetic retinopathy and neuropathy. Thus, we aimed at studying patients with long-standing type 2 diabetes mellitus who were prone to have detectable and gradable diabetic retinopathy and evaluate a possible association with sensitive measures of diabetic neuropathy.
Subjects and methods: The population-based cohort study included patients from the Split-Dalmatia county,...
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Crijevna mikrobiota aktivira prokarcinogen BBN
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Elena Ćosić UVOD: Svrha istraživanja je bila utvrditi povezanost mikrobioma s pojavom tumora mokraćnog mjehura izazvanog konzumacijom BBN-a (N-butil-N-(4-hidroksibutil) nitrozamin).
MATERIJALI I METODE: Istraživanje je provedeno na miševima C57BL/6J divljeg tipa podijeljenim u 5 skupina: akutni model dvotjednog tretmana BBN-om (“B” - miševi koji su konzumirali 0,05% otopinu BBN-a u vodi za piće kroz dva tjedna), akutni model tretmana 2+2tj BBN/antibiotici (AB - dvotjedni predtretman...
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Croatian translation and validation of the Sarcopenia Quality of Life Questionnaire
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Andrija Jukić Objectives: The aim of this study was to translate the official Sarcopenia Quality of Life questionnaire into Croatian language so that it is understandable for patients to answer it, after which we obtained the answers to assess further on how sarcopenia affects their lives through 7 different domains.
Materials and methods: The translated SarQoL questionnaire was given to 51 patient, all of whom were older than 65 and had a diagnosis of sarcopenia according to the European Working...
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Cytotoxic effect of thieno[2,3-b]pyridine derivatives on human bladder cancer cells
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Denis Kalezić Objectives: The purpose of this study was to determine the effects of treating bladder cancer cells with the newly synthesized thieno[2,3-b]pyridine anticancer agents, by focusing on its cytotoxic effects on the investigated human cell line T24.
Methods: The T24 bladder cancer cell line was treated with a newly developed thieno[2,3-b]pyridine anticancer compounds: Inhibitor 5 3-amino-N-(3-chloro-2-methylphenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide, Inhibitor 6...
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DO MEDICAL, DENTAL, AND PHARMACY STUDENTS BELIEVE THE BACK PAIN
MYTHS?
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Kristin Laura Walters Objectives: The aim of this study was to examine the attitudes and beliefs of medical students in
English and in Croatian, Dental medicine, and Pharmacy students at the University of s split school
of medicine (USSM) in Split, Croatia and the extent to which the back pain myths were accepted.
Materials and Methods: A cross-sectional study was carried out amongst the student population
enrolled at USSM. An online questionnaire was administered to 1,100 students in all academic
years...
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