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The influence of sexual behaviour, attitude and awareness of sexual health on self-esteem in medical students
The influence of sexual behaviour, attitude and awareness of sexual health on self-esteem in medical students
Ivona Matulić
Objective: This study aimed to examine the connections between self-esteem, gender, and attitudes towards sexuality and contraception in medical students. Specifically, the influence of self-esteem on gender-based differences in these attitudes was investigated. Methods: Cross-sectional study conducted from March to May 2023, the study involved 347 medical students from Croatian and English programs across all years. Participants provided informed consent and completed online...
The influence of thyroid functional parameters on thromboembolic events: a retrospective analysis
The influence of thyroid functional parameters on thromboembolic events: a retrospective analysis
Ina Grossmann
Objectives: Thyroid hormones are known to have numerous actions on body systems and functions, but their influence on blood coagulation and thrombus formation and therefore being a risk factor for developing a stroke, is less commonly discussed. The aim of this study is to observe if there could be a possible connection between thyroid functional parameters and the occurrence of a stroke, by investigating numerous laboratory parameters. We hypothesize that patients that experienced a stroke...
The prevalence of atherosclerosis in a population of Croatian islands - the use of the ankle-brachial pressure index (ABPI)
The prevalence of atherosclerosis in a population of Croatian islands - the use of the ankle-brachial pressure index (ABPI)
Ferdinand Klaus Schulenburg
Objectives: The objectives of this thesis are to investigate the patterns of ankle-brachial pressure index (ABPI) in the population of two Adriatic islands and the city of Split, and to determine the relationship between ABPI and key cardiovascular risk factors including blood pressure, serum lipids, and sedentary lifestyle. Methods: This thesis uses data from the 10,001 Dalmatians project and in total included data from 2,921 subjects. Of these, 991 subjects originated from the...
The reporting quality of abstracts of randomized controlled trials on Ginkgo biloba
The reporting quality of abstracts of randomized controlled trials on Ginkgo biloba
Marie Tintinger
Objectives: The aim of the study was to analyze Ginkgo biloba RCT abstracts publicly available on PubMed using the CONSORT checklist. Patients and Methods: A PubMed search for all RCTs on Gingko biloba was performed. The search strategy used the term ‘Gingko biloba` and the term ‘randomized controlled trial’ as article type. Inclusion criteria was abstract`s availability. The search was carried out in January 2020. To assess the reporting quality of analyzed abstracts, the 16...
The reporting quality of abstracts of randomized controlled trials on melatonin
The reporting quality of abstracts of randomized controlled trials on melatonin
Dzenisa Peco
Objectives: The goal of this study was to analyze the quality of abstracts of RCTs regarding melatonin and sleep disorders. Materials and methods: This study assessed the reporting quality of abstracts on PubMed for melatonin and sleep RCTs. A search yielded 232 abstracts, with 13 exclusions. The CONSORT for abstracts checklist was used to assess various aspects including study design, methods, results and conclusions. Data was analyzed using MedCalc software. Results: Of the 232...
The reporting quality of randomized  controlled trial abstracts on  topical vitamin C
The reporting quality of randomized controlled trial abstracts on topical vitamin C
Patricia Katharina Granic
Objectives: The aim of this study was to assess the reporting quality of randomized controlled trial abstracts on topical vitamin C. Materials and Methods: We conducted a comprehensive analysis of randomized controlled trials focused on local vitamin C. The quality of abstracts was assessed using the CONSORT checklist, which consists of 17 items. Results: During the observation period, there was no significant increase in the number of studies on the topical use of vitamin C...
The risk of sudden cardiac death and use of SGLT2 inhibitors in patients with heart failure and effect on major outcomes with respect to etiology of cardiomyopathy : a meta analysis of pivotal randomized controlled trials
The risk of sudden cardiac death and use of SGLT2 inhibitors in patients with heart failure and effect on major outcomes with respect to etiology of cardiomyopathy : a meta analysis of pivotal randomized controlled trials
Julia Kitty Berntsen
Objectives: The present study aimed to examine the impact of SGLT2 inhibitor added to optimal medical therapy on the rates of sudden cardiac death (SCD) events among outpatients with heart failure, compared to placebo. Furthermore, we sought to investigate the potential differential impact of SGLT2 inhibitor with respect to etiology of heart failure (ischemic vs. non-ischemic cardiomyopathy) in HF patients treated with SGLT2 inhibitor. Patients and methods: Meta-analysis examined...
The role of early high-dose rosuvastatin loading in patients presenting with acute coronary syndromes without persistent ST-segment elevation
The role of early high-dose rosuvastatin loading in patients presenting with acute coronary syndromes without persistent ST-segment elevation
Mette Leth-Olsen
Objectives: The present study aimed to examine the impact of early high-dose rosuvastatin loading (pretreatment) vs. no loading or placebo on short-term adverse outcomes at 30 days in statin-naive patients with acute coronary syndromes without persistent ST-segment elevation (NSTE-ACS) undergoing percutaneous coronary intervention (PCI). Patients and methods: Quantitative analysis and meta-analysis were performed by including five randomized controlled trials (RCTs) that examined the use...
The role of necroptosis in bladder cancer
The role of necroptosis in bladder cancer
Benedikt Eduard Haupt
Objectives: Although great progress has been achieved in terms of bladder cancer management, survival rates for muscle invasive bladder cancer are still dismal, which warrants for the search of new therapeutic approaches. Necroptosis is a programmed type of cell death, whose role has not been fully elucidated in bladder cancer. The objective of this study is to assess the prevalence of necroptosis at different time points during tumor progression and to investigate whether induction or...
The role of olfaction in dietary preferences, composition and anthropometric characteristics in the population of Dalmatia
The role of olfaction in dietary preferences, composition and anthropometric characteristics in the population of Dalmatia
Yasmin Lundström
Objectives: To assess the association between the ability to identify odors and anthropometric characteristics, as well as dietary preferences and diet composition in a large population-based sample. Materials and Methods: Examinees from the city of Split, and two settlements on the Island of Korcula (Smokvica and Blato) were included in this cross-sectional study. Anthropometric indices included in the analyses were BMI, waist circumference, waist-to-hip ratio, brachial width and neck...
The significance of calcium metabolism in uric acid stone formers
The significance of calcium metabolism in uric acid stone formers
Sebastian Tobias Königsberger
Introduction: Uric acid urolithiasis, a prevalent type of urinary stone disease, poses significant healthcare challenges. Effective treatment requires an understanding of factors contributing to stone formation and recurrence. We conducted a single-center observational study to explore these factors. Objectives: Our study aimed to investigate the relationship between specific demographic and clinical variables and the recurrence of uric acid urolithiasis. We hypothesized that factors...
The use of Inari FlowTriever® aspiration thrombectomy device for the management of acute pulmonary embolism : Initial experiences at the University Hospital of Split
The use of Inari FlowTriever® aspiration thrombectomy device for the management of acute pulmonary embolism : Initial experiences at the University Hospital of Split
Therese Gangestad Hafsmo
Objectives: Acute pulmonary embolism is a common medical emergency associated with a high risk of early mortality. The present thesis aimed to examine and describe the cohort of patients with acute pulmonary embolism (PE) who underwent catheter-directed percutaneous mechanical thromboaspiration with INARI FlowTriever® device and to assess safety and feasibility of this interventional method in this group of patients. Patients and methods: We retrospectively analyzed hospital records of...

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