Paginacija

The reporting quality of randomized  controlled trial abstracts on  topical vitamin C
The reporting quality of randomized controlled trial abstracts on topical vitamin C
Patricia Katharina Granic
Objectives: The aim of this study was to assess the reporting quality of randomized controlled trial abstracts on topical vitamin C. Materials and Methods: We conducted a comprehensive analysis of randomized controlled trials focused on local vitamin C. The quality of abstracts was assessed using the CONSORT checklist, which consists of 17 items. Results: During the observation period, there was no significant increase in the number of studies on the topical use of vitamin C...
The risk of sudden cardiac death and use of SGLT2 inhibitors in patients with heart failure and effect on major outcomes with respect to etiology of cardiomyopathy : a meta analysis of pivotal randomized controlled trials
The risk of sudden cardiac death and use of SGLT2 inhibitors in patients with heart failure and effect on major outcomes with respect to etiology of cardiomyopathy : a meta analysis of pivotal randomized controlled trials
Julia Kitty Berntsen
Objectives: The present study aimed to examine the impact of SGLT2 inhibitor added to optimal medical therapy on the rates of sudden cardiac death (SCD) events among outpatients with heart failure, compared to placebo. Furthermore, we sought to investigate the potential differential impact of SGLT2 inhibitor with respect to etiology of heart failure (ischemic vs. non-ischemic cardiomyopathy) in HF patients treated with SGLT2 inhibitor. Patients and methods: Meta-analysis examined...
The role of early high-dose rosuvastatin loading in patients presenting with acute coronary syndromes without persistent ST-segment elevation
The role of early high-dose rosuvastatin loading in patients presenting with acute coronary syndromes without persistent ST-segment elevation
Mette Leth-Olsen
Objectives: The present study aimed to examine the impact of early high-dose rosuvastatin loading (pretreatment) vs. no loading or placebo on short-term adverse outcomes at 30 days in statin-naive patients with acute coronary syndromes without persistent ST-segment elevation (NSTE-ACS) undergoing percutaneous coronary intervention (PCI). Patients and methods: Quantitative analysis and meta-analysis were performed by including five randomized controlled trials (RCTs) that examined the use...
The role of necroptosis in bladder cancer
The role of necroptosis in bladder cancer
Benedikt Eduard Haupt
Objectives: Although great progress has been achieved in terms of bladder cancer management, survival rates for muscle invasive bladder cancer are still dismal, which warrants for the search of new therapeutic approaches. Necroptosis is a programmed type of cell death, whose role has not been fully elucidated in bladder cancer. The objective of this study is to assess the prevalence of necroptosis at different time points during tumor progression and to investigate whether induction or...
The role of olfaction in dietary preferences, composition and anthropometric characteristics in the population of Dalmatia
The role of olfaction in dietary preferences, composition and anthropometric characteristics in the population of Dalmatia
Yasmin Lundström
Objectives: To assess the association between the ability to identify odors and anthropometric characteristics, as well as dietary preferences and diet composition in a large population-based sample. Materials and Methods: Examinees from the city of Split, and two settlements on the Island of Korcula (Smokvica and Blato) were included in this cross-sectional study. Anthropometric indices included in the analyses were BMI, waist circumference, waist-to-hip ratio, brachial width and neck...
The significance of calcium metabolism in uric acid stone formers
The significance of calcium metabolism in uric acid stone formers
Sebastian Tobias Königsberger
Introduction: Uric acid urolithiasis, a prevalent type of urinary stone disease, poses significant healthcare challenges. Effective treatment requires an understanding of factors contributing to stone formation and recurrence. We conducted a single-center observational study to explore these factors. Objectives: Our study aimed to investigate the relationship between specific demographic and clinical variables and the recurrence of uric acid urolithiasis. We hypothesized that factors...
The use of Inari FlowTriever® aspiration thrombectomy device for the management of acute pulmonary embolism : Initial experiences at the University Hospital of Split
The use of Inari FlowTriever® aspiration thrombectomy device for the management of acute pulmonary embolism : Initial experiences at the University Hospital of Split
Therese Gangestad Hafsmo
Objectives: Acute pulmonary embolism is a common medical emergency associated with a high risk of early mortality. The present thesis aimed to examine and describe the cohort of patients with acute pulmonary embolism (PE) who underwent catheter-directed percutaneous mechanical thromboaspiration with INARI FlowTriever® device and to assess safety and feasibility of this interventional method in this group of patients. Patients and methods: We retrospectively analyzed hospital records of...
The use of systematic reviews in randomized controlled trials in anesthesiology
The use of systematic reviews in randomized controlled trials in anesthesiology
Anja Engelking
Objectives: Systematic reviews (SRs) summarize current knowledge on a certain clinical question. To avoid research waste, new randomized clinical trials (RCTs) should be initiated if previous SRs indicate that there is no such evidence or that there is insufficient evidence from previous RCTs. The objective of this study was to analyze whether previous SRs are mentioned in RCTs published in anesthesiology journals as a rationale for conducting the RCT and for discussing the results. ...
Thrombectomy outcomes in middle cerebral artery stroke among the patients at the University hospital of Split
Thrombectomy outcomes in middle cerebral artery stroke among the patients at the University hospital of Split
Christopher Caap
Objectives: The aim of our study was to investigate if EVT for acute stroke caused by occlusion of MCA is as efficient in low volume centers as it is in clinical trials. Furthermore, to identify whether any previous comorbidities or treatments have an impact on clinical outcome or thrombectomy outcome within the population of the University Hospital Split, in Croatia. Materials and methods: A retrospective cohort study was carried out during 2020 of Neurology department in University...
Timske uloge studenata dentalne medicine, medicine i zdravstvenih studija
Timske uloge studenata dentalne medicine, medicine i zdravstvenih studija
Silvia Skorić
Cilj: Cilj ovog istraživanja bio je ispitati i usporediti psihološke odrednice i timske uloge studenata dentalne medicine, medicine i odjela zdravstvenih studija sveučilišta u Splitu. Materijali i metode: Podatci su prikupljeni provedbom anketnog istraživanja provedenog na ukupno 199 studenata (40 sa studija dentalne medicine, 73 sa studija medicine te 86 sa zdravstvenih studija). Podatci su analizirani prema studiju i spolu, korištenjem hi-kvadrat testa, t-testa i analize...
Tireotoksikoza u djece i adolescenata
Tireotoksikoza u djece i adolescenata
Frane Paleka
Cilj istraživanja: Utvrditi incidenciju tirotoksikoze u populaciji djece i adolescenata lijeĉenih na podruĉju Splitsko-dalmatinske ţupanije. Ispitati postoji li razlika u pojavnosti tirotoksikoze s obzirom na spol i dob pacijenta. Ispitati postotak remisije i relapsa tireotoksikoze u pacijenata mlaĊih od 18. godina. Odrediti indikacije i vrijeme za zbrinjavanje hipertireoze radiojodnom terapijom ili operacijskim zahvatom. Materijali i metode: Za izradu ovog diplomskog rada su...
Tissue characteristics in retinal surface disorders
Tissue characteristics in retinal surface disorders
Arun Joseph
Objectives: The objective of this study was to analyze the tissue characteristics in retinal surface disorders in four groups of patients including iERM, macular rupture, retinal detachment and diabetic retinopathy. It was hypothesised that VEGF is more expressed in less differentiated cells which should also show an overexpression of NESTIN. Materials and methods: ERM samples were collected over 4 years from 157 patients whose age group ranged between 12 and 82 years. The median age was...

Paginacija