Objectives: To investigate the associations of addiction substances in violent deaths in Split-Dalmatia County in the period from 2004. to 2014. to analyse all violent deaths in which toxicology analysis conducted in the presence of addictive substances in the blood and in biological fluids and tissues and to compare the obtained results with the results of similar studies in other areas of the Croatian and the world and to identify any discrepancies. Sources and methods: The research was conducted as an intersection study. We collected the data analysis archives of violent deaths and autopsied at the Clinical Department of Forensic Medicine, Institute of Pathology, Forensic Medicine and Cytology, Clinical Hospital Split, in Split-Dalmatia County in the period from 1 June 2004 and 1 June 2014. Our research includes violent deaths that were autopsied and toxicological analysis for the presence of alcohol and addictive substances in the blood and biological fluids and tissues. The parameters were observed for the circumstances of violent deaths are a place of death and the time of year (quarters). Parameters used for the analysis of victims of sex, age, alcohol concentration and the presence of addictive substances. Results: In the period from 1 June 2004 to 1 June 2014 in Split-Dalmatia County the most deaths were in 2007, and at least in 2012. Most of the dead were men. Most violent deaths were in III. quarter of the year (in the summer months from July to September). By comparing suicides and murders, significantly more were suicides t-test = 8.442406; p = 0.000075. Comparison of suicides and accidents, significantly more were accidents; The t-test = 3.56415; p = 0.005934. Among all categories: suicide, homicide, accidents and undetermined, there is a positive correlation between the number of deceased with alcohol concentration to 0.5 g / kg and the number of deceased with a higher concentration of alcohol of 0.5 g / kg. Ie. There was no statistically significant difference between men and women due to the ratio of the number of sober (alcohol concentration from 0.00 to 0.50 g/kg body weight) and intoxicated (alcohol concentration higher than 0.50 g/kg body weight) in person time of death: χ2 = 1.035; p = 0.30898. There was no statistically significant difference between the groups of deceased suicide and murder, and given the presence of addictive substances. χ 2 = 5.76; p = 0.2178. However, there is a statistically significant difference between the number of deceased by accident and the number of deceased in a group of suicide and murder together, and considering the presence of addictive substances. χ 2 = 28,586; p = 0.00007285. For murder victims the most common causes of death with sober and intoxicated and in people who were under the influence of addictive substances are mechanical causes. With suicide the most common causes of death among sober and intoxicated the mechanically while the persons who were under the influence of addictive substances asphyctic causes. When a person killed by accident the most common causes of death among sober, intoxicated or in people who were under the influence of addictive substances are mechanical. For people whose manner of death has not been determined the most common causes of death among sober, intoxicated or in people who were under the influence of addictive substances are mechanical. Conclusions: Most violent deaths were in 2007, and at least in 2012, most of the dead were men. Most of the victims died in III. quarter, during the summer and the most of them were accidents. More people were sober at the time of death and the most common cause of death in people who were sober, drunk or under the influence of addictive substances, were accidents. For murder victims that were sober, drunk or under the influence of addictive substances is the most common mechanical cause of death. The most common cause of death in people who have committed suicide while they were sober or drunk, was mechanically, and for people who were under the influence of addictive substances asphyctic cause of death. People who died in accidents the most common cause of death while they were sober, drunk or in people who were under the influence of addictive substances was mechanically. For people whose type of death has not been determined the most common cause of death while they were sober, drunk or in people who were under the influence of addictive substances mechanically.