Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow

Chacon Arenas, Diego Fernando

prikaz prve stranice dokumenta Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow

diplomski rad

Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow

2020. urn:nbn:hr:171:330241

Chacon Arenas, Diego Fernando

Sveučilište u Splitu
Medicinski fakultet
Anesteziologija i intenzivna medicina

Citirajte ovaj rad

APA 6th Edition

Chacon Arenas, D. F. (2020). Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow (Diplomski rad). Split: Sveučilište u Splitu, Medicinski fakultet. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:171:330241

MLA 8th Edition

Chacon Arenas, Diego Fernando. "Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow." Diplomski rad, Sveučilište u Splitu, Medicinski fakultet, 2020. https://urn.nsk.hr/urn:nbn:hr:171:330241

Chicago 17th Edition

Harvard

Chacon Arenas, D. F. (2020). 'Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow', Diplomski rad, Sveučilište u Splitu, Medicinski fakultet, citirano: 14.04.2024., https://urn.nsk.hr/urn:nbn:hr:171:330241

Vancouver

Chacon Arenas DF. Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow [Diplomski rad]. Split: Sveučilište u Splitu, Medicinski fakultet; 2020 [pristupljeno 14.04.2024.] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:171:330241

IEEE

D. F. Chacon Arenas, "Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow", Diplomski rad, Sveučilište u Splitu, Medicinski fakultet, Split, 2020. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:171:330241

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Podaci o radu

Naslov	Comparison of the frequency and intensity of the systemic inflammatory response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow
Naslov (hrvatski)	Usporedba učestalosti i intenziteta sustavnog upalnog odgovora u bolesnika podvrgnutih revaskularizacijskom zahvatu srčanog mišića sa i bez primjene ekstrakorporalnog krvotoka
Autor	Diego Fernando Chacon Arenas
Mentor	Mihajlo Lojpur (mentor)
Član povjerenstva	Mladen Carev (predsjednik povjerenstva)
Član povjerenstva	Božidar Duplančić (član povjerenstva)
Član povjerenstva	Zenon Pogorelić (član povjerenstva)
Ustanova koja je dodijelila akademski / stručni stupanj	Sveučilište u Splitu Medicinski fakultet (Anesteziologija i intenzivna medicina) Split
Datum i država obrane	2020-07-23, Hrvatska
Znanstveno / umjetničko područje, polje i grana	BIOMEDICINA I ZDRAVSTVO Kliničke medicinske znanosti Anesteziologija i reanimatologija
Sažetak	Objectives: The aim of this study was to investigate and compare the degree of the Systemic Inflammatory Response in patients undergoing CABG surgery with and without the use of cardiopulmonary bypass, with an additional focus on investigating the association between inflammatory indicators of SIRS and postoperative hospitalization length, morbidity, and mortality after cardiac surgery. Patients and methods: This study enrolled 30 patients, aged between 52 and 83 years, who were scheduled for elective CABG surgery with or without CPB. Allocation of patients into either group was based on the judgement of the surgical team. Patient leukocyte count, CRP level, PCT level, and number of SIRS criteria were determined before surgery and on the 1st, 2nd, 3rd and 5th postoperative days. Results: Postoperative leukocyte counts were elevated but remained in the ULN. On the contrary, CRP and PCT levels were markedly beyond normal range in the majority of measurements. However, no significant difference in the postoperative leukocyte count, CRP levels, and PCT levels between cardiac surgery with and without CPB was observed. No significant positive correlation was found between higher inflammatory indicators of SIRS and postoperative hospitalization length, morbidity, and mortality. Conclusion: CABG surgery with and without cardiopulmonary bypass are associated with a similar Systemic Inflammatory Response. Hospital stay, morbidity, and mortality after cardiac surgery is the same regardless of the presence of CPB. Our study failed to demostrate any difference in the frequency and intensity of the Systemic Inflammatory Response in patients undergoing cardiac muscle revascularization surgery with and without the use of extracorporeal blood flow.
Sažetak (hrvatski)	Ciljevi: Cilj ove studije bio je istražiti i usporediti stupanj sistemskog upalnog odgovora kod pacijenata koji su podvrgnuti CABG operaciji sa i bez upotrebe kardiopulmonalne zaobilaznice, s dodatnim fokusom na ispitivanje povezanosti između pokazatelja upale SIRS-a i duljine postoperativne hospitalizacije, morbiditeta , i smrtnost nakon srčane operacije. Spitanici i postupci: Ovo je istraživanje obuhvatilo 30 pacijenata, starih između 52 i 83 godine, kojima je bila predviđena izborna operacija CABG-a sa ili bez CPB-a. Raspodjela pacijenata u bilo koju skupinu temeljila se na prosudbi kirurškog tima. Broj leukocita bolesnika, razina CRP-a, razina PCT-a i broj SIRS kriterija određeni su prije operacije i 1., 2., 3. i 5. postoperativni dan. Rezultati: Postoperativni broj leukocita je povišen, ali ostao je u ULN-u. Suprotno tome, u većini mjerenja razina CRP i PCT bila je znatno iznad normalnog raspona. Međutim, nije primijećena značajna razlika u postojperativnom broju leukocita, razini CRP-a i PCT-u između srčane kirurgije sa i bez CPB-a. Nije utvrđena značajna pozitivna povezanost između viših upalnih pokazatelja SIRS-a i duljine postoperativne hospitalizacije, morbiditeta i smrtnosti. Zaključak: Operacija CABG-a sa i bez kardiopulmonalnog bajpasa povezana je sa sličnim sistemskim upalnim odgovorom. Boravak u bolnici, morbiditet i smrtnost nakon kardiološkog zahvata isti su bez obzira na prisutnost CPB-a. Naša studija nije uspjela utvrditi nijednu razliku u učestalosti i intenzitetu sistemskog upalnog odgovora kod pacijenata koji su bili podvrgnuti revaskularizaciji srčanog mišića sa i bez korištenja ekstrakorporalnog protoka krvi.
Ključne riječi
Ključne riječi (hrvatski)
Jezik	engleski
URN:NBN	urn:nbn:hr:171:330241
Studijski program	Naziv: Medicina na engleskom jeziku Vrsta studija: sveučilišni Stupanj studija: integrirani preddiplomski i diplomski Akademski / stručni naziv: doktor/doktorica medicine (dr. med.)
Vrsta resursa	Tekst
Način izrade datoteke	Izvorno digitalna
Prava pristupa	Otvoreni pristup
Uvjeti korištenja
Datum i vrijeme pohrane	2020-09-28 10:34:37