Objectives: The aim of this study was to compare frequency of renal cell carcinoma diagnosed in patients before and during the Covid-19 pandemic. Material and Methods: This study included 222 medical reports with patohistological confirmation of renal cell carcinoma at the Clinical Department of pathology, forensic medicine and cytology at the University Hospital Center Split in the period before the Covid-19 pandemic (January 1, 2019 – March 1, 2020) and during pandemic (March 1, 2020 – December 31, 2021). Objectives of this study were to analyze and compare the extent of the disease and the type of surgery preformed, as well as the demographics and patohistological characteristics of renal cell carcinoma diagnosed in patients before and during the Covid-19 pandemic. Results: Of the total number of kidney carcinoma (n=222), 117 were diagnosed in the year before Covid-19 pandemic, while the remaining 105 cancers were reported in the year during Covid-19 pandemic. In both groups results show higher incidence of renall cell carcinoma in men than women. The median age in the year before pandemic was 67 years, while it dropped in the year during pandemic on 65 years, which is statistically significant. Five partial nephrectomies were preformed in the year before Covid-19 pandemic, while in the year of the pandemic 15 partial nephrectomies were preformed, which is statistically significant increase. Total nephrectomy is the most common preformed procedure in both groups. In the year before the pandemic, zero papillary renal cell carcinomas type II and 1 oncocytoma were diagnosed, while in the year of pandemic, 8 papillary renal cell carcinomas type II and 7 oncocytomas were detected, which is statistically significant. At the time of diagnosis in both study groups, the largest number of patients was in the first stage of diseas, and the smallest number of patients had advanced disease with metastases. Conclusion: In the observed period during the Covid-19 pandemic, there was a slight decrease in the number of newly detected renal cell carcinomas,but there were no significant deviationts in the demographics and patohistological characteristics in patients with renal cell carcinoma compared to patients diagnosed with cancer in the year before the Covid-19 pandemic.