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The association between thyroid parameters and insulin resistance in patients with autoimmune thyroid disease
The association between thyroid parameters and insulin resistance in patients with autoimmune thyroid disease
Paul Philipp Kastner
Objectives: Our main goal was to observe associations between laboratory thyroid parameters free triiodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating-hormone (TSH), thyroid peroxidase antibodies (TPOAbs), thyroglobulin antibodies (TgAbs), deiodinase activity (SPINA-GD), thyrotroph thyroid resistance index (TTSI), thyroid stimulating hormone index (TSHI), and the homeostatic model assessment of insulin resistance (HOMA-IR). We were particularly interested in comparing these...
The correlation between adenoid hypertrophy and chronic otitis media with effusion in children
The correlation between adenoid hypertrophy and chronic otitis media with effusion in children
Marta Vucemilovic
Objectives: The purpose of this study is to confirm whether there is a correlation between adenoid hypertrophy and the incidence of otitis media with effusion in children that are of school age or younger. Additionally, this study aims to clarify which age groups are at greater risk in having high grade adenoid hypertrophy associated with otitis media with effusion, and which are the most common presenting symptoms among those patients. Methods: Sixty- five patients aged 2-12 years old were...
The correlation between results in different domains of cogitive abilities in medical students
The correlation between results in different domains of cogitive abilities in medical students
Aisha Qazzafi
Objectives: The aim of this study is to investigate the correlations between IQ test scores performed through the Raven’s Advanced Progressive Matrices (APM) and cognitive testing through the Complex Reactionmeter Drenovac (CRD) test battery. Subjects and methods: From 2017-2019, 224 medical students at the University of Split School of Medicine (USSM) studying in the English and Croatian programme were recruited for this study. The IQ scores of the students were assessed using...
The cytotoxic effect and apoptosis rate of breast cancer stem cells treated with the novel thieno[2,3-b]pyridine anticancer compound
The cytotoxic effect and apoptosis rate of breast cancer stem cells treated with the novel thieno[2,3-b]pyridine anticancer compound
Louisa Willmen
Objectives: The purpose of this study is to determine the effects of treating breast cancer stem cells with the newly synthesized thieno[2,3-b]pyridine anticancer agent, by focusing on its cytotoxic and apoptotic effects on the investigated human cell line MDA-MB-231. Methods: The MDA-MB-231 triple-negative breast cancer cell line was treated with a newly developed thienopyridine anticancer compound (3-amino-N-(3-chloro-2-methylphenyl)-5-...
The early outcome of thrombectomy in patients with basilar artery stroke
The early outcome of thrombectomy in patients with basilar artery stroke
Malin Charlotte Monsen Snarberg
Objective: The main purpose of this study was to evaluate the early outcome of patients with stroke caused by basilar artery occlusion after endovascular treatment – thrombectomy. The aim was also to determine whether there are some predictors of good outcome and to compare our results with already published data. Materials and methods: We included 16 patients with proven BAO treated with thrombectomy from the Department of Neurology in University Hospital Split in the timeframe...
The effect of physical therapy treatment on shoulder pain, mobility and functional index in the working population
The effect of physical therapy treatment on shoulder pain, mobility and functional index in the working population
Johanna Sophie Dirkwinkel
Objectives: Shoulder pain is reported to be one of the most common types of musculoskeletal pain and known for causing numerous days of sick leave in the working population. Thus the aim of this study was to evaluate the effect of physical therapy on pain, mobility and functional index in order to find an appropriate treatment regimen to lessen the significant burden for the well-being of the patient and the health-care economics. Methods: A clinical trial was performed between March and...
The effect of preprocedural application of topical medications on the radial artery dilation and occurrence of vasospasm in patients undergoing transradial angiography
The effect of preprocedural application of topical medications on the radial artery dilation and occurrence of vasospasm in patients undergoing transradial angiography
Lisa Fylling
Objectives: The present study aimed to examine whether the application of a topical cutaneous medication, compared to standard subcutaneous lidocaine infiltration, prior to radial artery puncture in the setting of diagnostic coronary angiography will impact the occurrence of radial artery spasm, pain experienced by the patient during the procedure, and mean attempts of radial artery cannulation. Patients and methods: Cumulative meta-analysis of data derived from 7 randomized controlled or...
The effects of long-term diabetes mellitus on adult neurogenesis in subventricular zone of the rat brain
The effects of long-term diabetes mellitus on adult neurogenesis in subventricular zone of the rat brain
Tim Hendrik Boy
Objectives: Diabetes mellitus has been associated with increased risk of cognitive decline, dementia, depression and anxiety. The aims of this study were to determine the influence of aging and long-term type 1 diabetes mellitus (DM1) on the rate of adult neurogenesis in subventricular zone of rats, as well as to determine the possible role of DSTYK protein in the adult neurogenesis in subventricular zone of rats as a possible disease mechanism. Material and Methods: Thirty-five male...
The effects of moderate daily red wine intake on arterial stiffness and hemodynamic parameters in type 2 diabetes mellitus
The effects of moderate daily red wine intake on arterial stiffness and hemodynamic parameters in type 2 diabetes mellitus
Anika Katarina Januš
Introduction: Type 2 Diabetes Mellitus (T2DM) is a prevalent cause of morbidity and mortality, particularly due to chronic complications development, most commonly cardiovascular diseases. Among markers for assessment of clinical and subclinical signs of cardiovascular disease, the presence of arteriosclerosis, and stiffening of arterial walls as indicated by the arterial stiffness, was proven to be an important predictor of adverse cardiovascular events. Carotid-femoral pulse wave velocity...
The expression of Pannexin 1 in the developing human spinal cord and dorsal root ganglia
The expression of Pannexin 1 in the developing human spinal cord and dorsal root ganglia
Julia Christina Zeitler
Objectives: The objective of this study was to explore the expression of Pannexin 1 (Panx1) in the spinal cord (SC) and ganglia of human conceptus during early phase of intrauterine development. Material and methods: The human conceptus tissue was collected from the Department of Gynecology and Obstetrics and the Department of Pathology after tubal pregnancies or after spontaneous abortions. The immunohistochemistry procedure was used to visualize the targeted proteins. The data...
The expression pattern of Notch2 and Dab1 in the postnatal kidney of Dab1-/- mice
The expression pattern of Notch2 and Dab1 in the postnatal kidney of Dab1-/- mice
Larissa Gudelj Ensor
Objectives: The expression and localization of Dab1 adaptor proteins and Notch2 receptors in the nephrons of yotari (Dab1 -/-), heterozygote (Dab1 +/-), and Wildtype (Dab1 +/+) mice was analyzed to further develop their suggested importance in mammal kidneys overall, but also their significance particularly in yotari mice nephrons. Materials and methods: yotari, heterozygote and wildtype mice were sacrificed on the 4th postnatal day. Paraffin embedded kidney tissue sections were analyzed...
The impact of location and amount of lung metastases in primary colorectal and renal cell cancer on prognosis : a retrospective observational study
The impact of location and amount of lung metastases in primary colorectal and renal cell cancer on prognosis : a retrospective observational study
Melissa Tanja Wieloch
Objectives: Aim of this study was to figure out whether localization and amount of lung metastases can influence the prognosis of the disease. Materials and methods: In this retrospective observational study all patients with newly diagnosed primary colorectal or renal cell carcinoma and only lung metastases administered to Regiomed clinic association between January 1, 2018 and February 1, 2022 were included. In total 35 patients were classified into groups according to primary type of...

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